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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8772-6_8
Abstract: The polarizing region of the developing limb bud is an important organizing center that is involved in anteroposterior (thumb to little finger) patterning and has three main functions that are now considered to depend on…
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Keywords:
tissue grafting;
polarizing region;
limb bud;
region ... See more keywords
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Published in 2021 at "Developmental biology"
DOI: 10.1016/j.ydbio.2021.12.016
Abstract: The chick limb bud has plasticity to reconstruct a normal skeletal pattern after a part of mesenchymal mass is excised to make a hole in its early stage of development. To understand the details of…
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Keywords:
anterior posterior;
limb bud;
hole;
normal skeletal ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0175673
Abstract: Limb bud patterning, outgrowth, and differentiation are precisely regulated in a spatio-temporal manner through integrated networks of transcription factors, signaling molecules, and downstream genes. However, the exact mechanisms that orchestrate morphogenesis of the limb remain…
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Keywords:
transcription;
limb;
expression;
limb bud ... See more keywords
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Published in 2017 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2017.00014
Abstract: The gene encoding the secreted protein Sonic hedgehog (Shh) is expressed in the polarizing region (or zone of polarizing activity), a small group of mesenchyme cells at the posterior margin of the vertebrate limb bud.…
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Keywords:
positional values;
limb;
antero posterior;
limb bud ... See more keywords