Articles with "limbal epithelial" as a keyword



Niche regulation of limbal epithelial stem cells: HC-HA/PTX3 as surrogate matrix niche.

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Published in 2020 at "Experimental eye research"

DOI: 10.1016/j.exer.2020.108181

Abstract: Homeostasis of the corneal epithelium is ultimately maintained by stem cells that reside in a specialized microenvironment within the corneal limbus termed palisades of Vogt. This limbal niche nourishes, protects, and regulates quiescence, self-renewal, and… read more here.

Keywords: limbal epithelial; epithelial stem; matrix; niche ... See more keywords

Computer simulation of neutral drift among limbal epithelial stem cells of mosaic mice

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Published in 2018 at "Stem Cell Research"

DOI: 10.1016/j.scr.2018.05.003

Abstract: The use of mice that are mosaic for reporter gene expression underlies many lineage-tracing studies in stem cell biology. For example, using mosaic LacZ reporter mice, it was shown that limbal epithelial stem cells (LESCs)… read more here.

Keywords: limbal epithelial; computer; epithelial stem; neutral drift ... See more keywords

Adipose-derived stem cells undergo differentiation after co-culture with porcine limbal epithelial stem cells.

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Published in 2019 at "Stem cell research"

DOI: 10.1016/j.scr.2019.101609

Abstract: Mesenchymal stem cells (MSCs) are objects of interest in regenerative medicine. They are used for various therapies such as for the regeneration of bone, chondrocytes and other tissues. Adipose derived stem cells (ADSCs) inter alia… read more here.

Keywords: limbal epithelial; porcine limbal; epithelial stem; differentiation ... See more keywords
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Autologous Serum Eye Drops Diluted with Cyclosporine A 0.05% and Sodium Hyaluronate 0.1%: An Experimental Comparative Study

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Published in 2024 at "Current Eye Research"

DOI: 10.1080/02713683.2024.2385442

Abstract: Abstract Purpose The purpose of this study was to assess in-vitro efficacy of a suffusion of autologous serum withcyclosporine 0.05% (CsA) and sodium hyaluronate 0.1% (SH). Methods The expression of proinflammatory markers interleukin 6 (IL-6)… read more here.

Keywords: sodium hyaluronate; serum; autologous serum; eye ... See more keywords

Pax6-induced proliferation and differentiation of bone marrow mesenchymal stem cells into limbal epithelial stem cells.

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Published in 2023 at "Stem cells and development"

DOI: 10.1089/scd.2022.0249

Abstract: Corneal integrity, transparency, and visual acuity are maintained by corneal epithelial cells (CECs), which are continuously renewed by limbal epithelial stem cells (LESCs). The limbal stem cell deficiency (LSCD) is associated with ocular diseases. This… read more here.

Keywords: marrow mesenchymal; bone marrow; limbal epithelial; stem ... See more keywords

Safety and Efficacy of Contact Lenses in Eyes After Simple Limbal Epithelial Transplantation.

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Published in 2023 at "Cornea"

DOI: 10.1097/ico.0000000000003228

Abstract: PURPOSE The aim of this study was to evaluate the safety and efficacy of contact lenses (CLs) in eyes after simple limbal epithelial transplantation (SLET) for limbal stem cell deficiency (LSCD). METHODS This retrospective study… read more here.

Keywords: contact lenses; safety efficacy; eyes simple; limbal epithelial ... See more keywords
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Simple limbal epithelial transplantation

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Published in 2017 at "Current Opinion in Ophthalmology"

DOI: 10.1097/icu.0000000000000377

Abstract: Purpose of review Simple limbal epithelial transplant (SLET) is a technique for addressing limbal stem cell deficiency. Limbal tissue from a donor eye, typically the patient's fellow healthy eye, is transplanted onto an amniotic membrane… read more here.

Keywords: limbal epithelial; simple limbal; ophthalmology; epithelial transplantation ... See more keywords

Midterm results after allogeneic simple limbal epithelial transplantation from deceased‐donor eyes in patients with persistent corneal epithelial defects due to limbal stem cell deficiency

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Published in 2024 at "Acta Ophthalmologica"

DOI: 10.1111/aos.16760

Abstract: This study aims to characterize the clinical outcomes after allogeneic simple limbal epithelial transplantation (alloSLET) utilizing tissue from cadaveric donor eyes to address persistent corneal epithelial defects caused by limbal stem cell deficiency. read more here.

Keywords: allogeneic simple; epithelial transplantation; persistent corneal; limbal epithelial ... See more keywords

Assessment of corneal and limbal epithelial thickness by spectral-domain optical coherence tomography in brachycephalic and non-brachycephalic dogs.

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Published in 2022 at "Veterinary ophthalmology"

DOI: 10.1111/vop.13016

Abstract: OBJECTIVE To investigate the variance in corneal epithelial thickness (CET) and limbal epithelial thickness (LET) according to the age and skull type by using spectral-domain optical coherence tomography (SD-OCT) in normal dogs. ANIMALS AND PROCEDURES… read more here.

Keywords: epithelial thickness; brachycephalic dogs; brachycephalic non; limbal epithelial ... See more keywords

Ex Vivo Expansion of Human Limbal Epithelial Cells Using Human Placenta-Derived and Umbilical Cord-Derived Mesenchymal Stem Cells

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Published in 2017 at "Stem Cells International"

DOI: 10.1155/2017/4206187

Abstract: Ex vivo culture of human limbal epithelial cells (LECs) is used to treat limbal stem cell (LSC) deficiency, a vision loss condition, and suitable culture systems using feeder cells or serum without animal elements have… read more here.

Keywords: stem cells; limbal epithelial; human limbal; stem ... See more keywords

Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis

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Published in 2023 at "F1000Research"

DOI: 10.12688/f1000research.133637.1

Abstract: Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring and thinning.… read more here.

Keywords: case report; limbal epithelial; transplantation; corneal ... See more keywords