Niche regulation of limbal epithelial stem cells: HC-HA/PTX3 as surrogate matrix niche.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental eye research"
DOI: 10.1016/j.exer.2020.108181
Abstract: Homeostasis of the corneal epithelium is ultimately maintained by stem cells that reside in a specialized microenvironment within the corneal limbus termed palisades of Vogt. This limbal niche nourishes, protects, and regulates quiescence, self-renewal, and… read more here.
Keywords: limbal epithelial; epithelial stem; matrix; niche ... See more keywords
Computer simulation of neutral drift among limbal epithelial stem cells of mosaic mice
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Research"
DOI: 10.1016/j.scr.2018.05.003
Abstract: The use of mice that are mosaic for reporter gene expression underlies many lineage-tracing studies in stem cell biology. For example, using mosaic LacZ reporter mice, it was shown that limbal epithelial stem cells (LESCs)… read more here.
Keywords: limbal epithelial; computer; epithelial stem; neutral drift ... See more keywords
Adipose-derived stem cells undergo differentiation after co-culture with porcine limbal epithelial stem cells.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cell research"
DOI: 10.1016/j.scr.2019.101609
Abstract: Mesenchymal stem cells (MSCs) are objects of interest in regenerative medicine. They are used for various therapies such as for the regeneration of bone, chondrocytes and other tissues. Adipose derived stem cells (ADSCs) inter alia… read more here.
Keywords: limbal epithelial; porcine limbal; epithelial stem; differentiation ... See more keywords
Pax6-induced proliferation and differentiation of bone marrow mesenchymal stem cells into limbal epithelial stem cells.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells and development"
DOI: 10.1089/scd.2022.0249
Abstract: Corneal integrity, transparency, and visual acuity are maintained by corneal epithelial cells (CECs), which are continuously renewed by limbal epithelial stem cells (LESCs). The limbal stem cell deficiency (LSCD) is associated with ocular diseases. This… read more here.
Keywords: marrow mesenchymal; bone marrow; limbal epithelial; stem ... See more keywords
Safety and Efficacy of Contact Lenses in Eyes After Simple Limbal Epithelial Transplantation.
Sign Up to like & getrecommendations! Published in 2023 at "Cornea"
DOI: 10.1097/ico.0000000000003228
Abstract: PURPOSE The aim of this study was to evaluate the safety and efficacy of contact lenses (CLs) in eyes after simple limbal epithelial transplantation (SLET) for limbal stem cell deficiency (LSCD). METHODS This retrospective study… read more here.
Keywords: contact lenses; safety efficacy; eyes simple; limbal epithelial ... See more keywords
Simple limbal epithelial transplantation
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Ophthalmology"
DOI: 10.1097/icu.0000000000000377
Abstract: Purpose of review Simple limbal epithelial transplant (SLET) is a technique for addressing limbal stem cell deficiency. Limbal tissue from a donor eye, typically the patient's fellow healthy eye, is transplanted onto an amniotic membrane… read more here.
Keywords: limbal epithelial; simple limbal; ophthalmology; epithelial transplantation ... See more keywords
Assessment of corneal and limbal epithelial thickness by spectral-domain optical coherence tomography in brachycephalic and non-brachycephalic dogs.
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary ophthalmology"
DOI: 10.1111/vop.13016
Abstract: OBJECTIVE To investigate the variance in corneal epithelial thickness (CET) and limbal epithelial thickness (LET) according to the age and skull type by using spectral-domain optical coherence tomography (SD-OCT) in normal dogs. ANIMALS AND PROCEDURES… read more here.
Keywords: epithelial thickness; brachycephalic dogs; brachycephalic non; limbal epithelial ... See more keywords
Ex Vivo Expansion of Human Limbal Epithelial Cells Using Human Placenta-Derived and Umbilical Cord-Derived Mesenchymal Stem Cells
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells International"
DOI: 10.1155/2017/4206187
Abstract: Ex vivo culture of human limbal epithelial cells (LECs) is used to treat limbal stem cell (LSC) deficiency, a vision loss condition, and suitable culture systems using feeder cells or serum without animal elements have… read more here.
Keywords: stem cells; limbal epithelial; human limbal; stem ... See more keywords
Case Report: Simultaneous penetrating keratoplasty with autologous simple limbal epithelial transplantation as an alternative to keratoprosthesis
Sign Up to like & getrecommendations! Published in 2023 at "F1000Research"
DOI: 10.12688/f1000research.133637.1
Abstract: Introduction and importance: This case report highlights the multidisciplinary approach required to achieve successful anatomical and functional outcomes, in an eye with total limbal stem cell deficiency (LSCD) associated with underlying corneal scarring and thinning.… read more here.
Keywords: case report; limbal epithelial; transplantation; corneal ... See more keywords
Modified Supportive Simple Limbal Epithelial Transplantation (M-SLET): A surgical technique modified for limbal stem cell deficiency
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_1891_22
Abstract: This study aimed to develop and modify the surgical technique of simple limbal epithelial transplantation in patients with limbal stem cell deficiency to provide support to epithelial explants during the post-operative period. This is a… read more here.
Keywords: slet; limbal epithelial; simple limbal; technique ... See more keywords
Innovative technique of mini-simple limbal epithelial transplantation in pediatric patients
Sign Up to like & getrecommendations! Published in 2021 at "Indian Journal of Ophthalmology"
DOI: 10.4103/ijo.ijo_2834_20
Abstract: In this article, we introduce a modified technique of minor ipsilateral simple limbal epithelial transplantation (mini-SLET) in pediatric patients of limbal stem cell deficiency (LSCD). Two children with unilateral partial LSCD underwent the innovative technique… read more here.
Keywords: pediatric patients; simple limbal; limbal epithelial; innovative technique ... See more keywords