MiR-134 modulates chronic stress-induced structural plasticity and depression-like behaviors via downregulation of Limk1/cofilin signaling in rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.01.009
Abstract: ABSTRACT Increasing evidence has suggested that depression is a neuropsychiatric condition associated with neuroplasticity within specific brain regions. However, the mechanisms by which neuroplasticity exerts its effects in depression remain largely uncharacterized. In the present… read more here.
Keywords: depression; limk1 cofilin; mir 134; like behaviors ... See more keywords
The abnormal phosphorylation of the Rac1, Lim-kinase 1, and Cofilin proteins in the pathogenesis of Hirschsprung’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2051882
Abstract: ABSTRACT Rac1 can affect the migration of neural crest cells by regulating the polymerization of actin and the membrane formation process. But the role of the Rac1 signaling pathway in the pathogenesis of Hirschsprung’s disease… read more here.
Keywords: rac1; group; limk1 cofilin; pathogenesis ... See more keywords
PAK2 promotes proliferation, migration, and invasion of lung squamous cell carcinoma through the LIMK1/cofilin signaling pathway
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biomedical Research"
DOI: 10.7555/jbr.37.20230317
Abstract: Although p21-activated kinase 2 (PAK2) is an essential serine/threonine protein kinase, its role in the progression of lung squamous cell carcinoma (LUSC) has yet to be fully understood. We analyzed PAK2 mRNA levels, DNA copy… read more here.
Keywords: cofilin signaling; limk1 cofilin; cell; invasion ... See more keywords