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   Articles with "lin28b" as a keyword



LIN28B regulates androgen receptor in human trophoblast cells through Let‐7c

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recommendations! Published in 2019 at "Molecular Reproduction and Development"

DOI: 10.1002/mrd.23226

Abstract: LIN28B is an RNA‐binding protein necessary for maintaining pluripotency in stem cells and plays an important role in trophoblast cell differentiation. LIN28B action on target gene function often involves the Let‐7 miRNA family. Previous work… read more here.

Keywords: lin28b; trophoblast; cells let; trophoblast cells ... See more keywords

A LIN28B Tumor-Specific Transcript in Cancer.

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recommendations! Published in 2018 at "Cell reports"

DOI: 10.1016/j.celrep.2018.02.002

Abstract: The diversity and complexity of the cancer transcriptome may contain transcripts unique to the tumor environment. Here, we report a LIN28B variant, LIN28B-TST, which is specifically expressed in hepatocellular carcinoma (HCC) and many other cancer… read more here.

Keywords: cancer; lin28b tumor; lin28b; lin28b tst ... See more keywords

LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression

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recommendations! Published in 2024 at "Leukemia"

DOI: 10.1038/s41375-024-02167-0

Abstract: TO THE EDITOR: Infant leukemias present within the fi rst year of life as either acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML). A majority are driven by KMT2A/MLL rearrangements (henceforth MLLr) that arise… read more here.

Keywords: mll enl; differentiation fully; lin28b; leukemia ... See more keywords
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The LIN28B/TGF-β/TGFBI feedback loop promotes cell migration and tumour initiation potential in cholangiocarcinoma.

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recommendations! Published in 2021 at "Cancer gene therapy"

DOI: 10.1038/s41417-021-00387-5

Abstract: Cholangiocarcinoma (CCA), a lethal malignancy of the biliary epithelium, is the second most common primary liver cancer. The poor prognosis of CCA is due to the high rate of tumour invasion and distant metastasis. We… read more here.

Keywords: lin28b; cell migration; cholangiocarcinoma; tgf ... See more keywords

Semaphorin 3A inhibits tumor progression via down-regulation of Lin28B in ovarian cancer.

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recommendations! Published in 2023 at "Neoplasma"

DOI: 10.4149/neo_2023_220206n139

Abstract: Semaphorin 3A (Sema3A) has recently been proven to play an essential role in tumorigenesis. Here, the role of Sema3A in ovarian cancer is explored. The prognostic value of Sema3A was evaluated using the Kaplan-Meier Plotter… read more here.

Keywords: ovarian cancer; lin28b; sema3a; regulation ... See more keywords