Cell stretchers and the LINC complex in mechanotransduction.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2021.108829
Abstract: How cells respond to mechanical forces from the surrounding environment is critical for cell survival and function. The LINC complex is a central component in the mechanotransduction pathway that transmits mechanical information from the cell… read more here.
Keywords: stretchers linc; linc complex; respond mechanical; mechanotransduction ... See more keywords
The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-84750-4
Abstract: The morphology of the Golgi complex is influenced by the cellular context, which strictly correlates with nuclear functions; however, the mechanism underlying this association remains elusive. The inner nuclear membrane SUN proteins, SUN1 and SUN2,… read more here.
Keywords: linc complex; kif20a; golgi; sun2 nesprin ... See more keywords
The Role of the LINC Complex in Sperm Development and Function
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21239058
Abstract: The LINC (LInker of Nucleoskeleton and Cytoskeleton) complex is localized within the nuclear envelope and consists of SUN (Sad1/UNc84 homology domain-containing) proteins located in the inner nuclear membrane and KASH (Klarsicht/Anc1/Syne1 homology domain-containing) proteins located… read more here.
Keywords: linc complex; complex sperm; role linc; development ... See more keywords
A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.60175
Abstract: The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex mechanically couples cytoskeletal and nuclear components across the nuclear envelope to fulfil a myriad of cellular functions, including nuclear shape and positioning, hearing, and meiotic chromosome movements.… read more here.
Keywords: linc complex; sun; structurally diverse; sun kash ... See more keywords