EM Tomography of Meiotic LINC Complexes.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8691-0_1
Abstract: Electron microscope (EM) tomography is a powerful technique that enables the three-dimensional analysis of subcellular structures at high resolution. We have applied this method to the quantitative analysis of LINC complex distribution and interaction with… read more here.
Keywords: meiotic linc; linc complexes; biology; tomography meiotic ... See more keywords
Genetic Analysis of Nuclear Migration and Anchorage to Study LINC Complexes During Development of Caenorhabditis elegans.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8691-0_13
Abstract: Studying nuclear positioning in developing tissues of the model nematode Caenorhabditis elegans greatly contributed to the discovery of SUN and KASH proteins and the formation of the LINC model. Such studies continue to make important… read more here.
Keywords: linc complexes; caenorhabditis elegans; migration; nuclear migration ... See more keywords
LINC complexes as regulators of meiosis.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2018.01.005
Abstract: Meiosis is a key processes of sexual reproduction in eukaryotes. By combining two cell division cycles with a single round of DNA replication meiosis provides a mechanism to generate haploid gametes. Coincidentally, processes involved in… read more here.
Keywords: linc complexes; complexes regulators; homologous chromosomes; regulators meiosis ... See more keywords
Conserved SUN-KASH Interfaces Mediate LINC Complex-Dependent Nuclear Movement and Positioning
Sign Up to like & getrecommendations! Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.08.001
Abstract: Many nuclear positioning events involve linker of nucleoskeleton and cytoskeleton (LINC) complexes, which transmit forces generated by the cytoskeleton across the nuclear envelope. LINC complexes are formed by trans-luminal interactions between inner nuclear membrane SUN… read more here.
Keywords: sun kash; kash; linc complexes; nuclear migration ... See more keywords
Mechanical LINCs of the nuclear envelope: Where SUN meets KASH
Sign Up to like & getrecommendations! Published in 2018 at "Extreme Mechanics Letters"
DOI: 10.1016/j.eml.2018.01.010
Abstract: Author(s): Jahed, Z; Mofrad, MRK | Abstract: © 2018 Elsevier Ltd The transmission of mechanical signals across the nuclear envelope is primarily mediated by linkers of the nucleoskeleton and cytoskeleton (LINC complexes). These complexes bridge… read more here.
Keywords: linc complexes; nuclear envelope; envelope; lincs nuclear ... See more keywords
Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-06-0467
Abstract: Different forms of nuclear envelope–spanning LINC complexes have opposing roles in the transcription-independent control of the small GTPase RhoA. Competition between LINC complexes in the nuclear envelope may therefore dictate the outcome of signaling to… read more here.
Keywords: linc complexes; opposing roles; gtpase rhoa; small gtpase ... See more keywords
Differential incorporation of SUN-domain proteins into LINC complexes is coupled to gene expression
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0197621
Abstract: LInkers of Nucleoskeleton and Cytoskeleton (LINC) complexes, composed of SUN and KASH-domain proteins, span the nuclear envelope and physically connect the nuclear interior to cytoskeletal elements. Most human cells contain two SUN proteins, Sun1 and… read more here.
Keywords: linc complexes; domain proteins; linc; gene expression ... See more keywords