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   Articles with "linc pint" as a keyword



Inhibition of Long Noncoding RNA Linc‐Pint by Hepatitis C Virus in Infected Hepatocytes Enhances Lipogenesis

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recommendations! Published in 2020 at "Hepatology"

DOI: 10.1002/hep.31656

Abstract: HCV often causes chronic infection in liver, cirrhosis, and, in some instances, HCC. HCV encodes several factors' those impair host genes for establishment of chronic infection. The long noncoding RNAs (lncRNAs) display diverse effects on… read more here.

Keywords: long noncoding; linc pint; lipogenesis; inhibition long ... See more keywords

PINTology: A short history of the lncRNA LINC‐PINT in different diseases

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recommendations! Published in 2022 at "Wiley Interdisciplinary Reviews: RNA"

DOI: 10.1002/wrna.1705

Abstract: LINC‐PINT is a p53‐induced long intergenic noncoding transcript that plays a crucial role in many diseases, especially cancer. This long noncoding RNA (lncRNA) gene produces in total 102 (LNCipedia) alternatively spliced variants (LINC‐PINT:1 to LINC‐PINT:102).… read more here.

Keywords: history lncrna; pint; linc pint; pintology short ... See more keywords

Assessment of LINC-PINT genetic polymorphisms and esophageal squamous cell carcinoma risk in the Hainan Han population

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recommendations! Published in 2024 at "Annals of Medicine"

DOI: 10.1080/07853890.2024.2397569

Abstract: Abstract Objectives Esophageal squamous cell carcinoma (ESCC) is a malignant tumor with high incidence and mortality rates worldwide. This study aimed to investigate the correlation between LINC-PINT polymorphisms and ESCC risk in the Hainan Han… read more here.

Keywords: escc risk; risk; linc pint; escc ... See more keywords

Functional Mechanism and Clinical Implications of lncRNA LINC-PINT in Delayed Fracture Healing

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recommendations! Published in 2024 at "Journal of Investigative Surgery"

DOI: 10.1080/08941939.2024.2421826

Abstract: Abstract Background Fracture healing can be impeded or even compromised by various factors, resulting in a growing number of patients suffering. The lncRNA LINC-PINT has garnered attention for its latent role in enhancing fracture healing,… read more here.

Keywords: linc pint; mir 324; fracture healing; pint ... See more keywords
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A lncRNA survey finds increases in neuroprotective LINC‐PINT in Parkinson’s disease substantia nigra

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recommendations! Published in 2020 at "Aging Cell"

DOI: 10.1111/acel.13115

Abstract: Recent reports highlight regulatory functions of long noncoding RNAs (lncRNAs) in neurodegeneration and aging, but biomedical implications remain limited. Here, we report an rRNA‐depletion‐based long RNA‐Sequencing Resource of 65 substantia nigra, amygdala, and medial temporal… read more here.

Keywords: linc pint; parkinson disease; substantia nigra; pint ... See more keywords

Long noncoding RNA LINC-PINT promotes proliferation through EZH2 and predicts poor prognosis in clear cell renal cell carcinoma

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recommendations! Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s202938

Abstract: Background: Renal cell carcinoma (RCC) is one of the most common types of urological malignant tumors. Despite recent advances in diagnosis and management of RCC, its prognosis remains poor. Emerging evidence has shown that long… read more here.

Keywords: linc pint; pint; cell; ezh2 ... See more keywords

Clinical implications of lncRNA LINC-PINT in cancer

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recommendations! Published in 2023 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2023.1097694

Abstract: Long noncoding RNAs (lncRNAs) possess the potential for therapeutic targeting to treat many disorders, including cancers. Several RNA-based therapeutics (ASOs and small interfering RNAs) have gained FDA approval over the past decade. And with their… read more here.

Keywords: clinical implications; lncrna linc; pint; linc pint ... See more keywords

LINC-PINT suppresses cisplatin resistance in gastric cancer by inhibiting autophagy activation via epigenetic silencing of ATG5 by EZH2

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.968223

Abstract: Resistance to cisplatin (DDP) is a major obstacle in the clinical treatment of advanced gastric cancer (GC). Long noncoding RNA (lncRNA) play a significant regulatory role in the development and drug resistance of GC. In… read more here.

Keywords: ezh2; pint; linc pint; ddp ... See more keywords