Blocking LINC00152 suppresses glioblastoma malignancy by impairing mesenchymal phenotype through the miR-612/AKT2/NF-κB pathway
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-018-2951-0
Abstract: IntroductionGlioblastoma, the most common and mortal primary brain tumor, accompanied with a dismal clinical outcome in adults. The oncogenic functions of long non-coding RNAs (lncRNAs) in glioblastoma have not been completely illuminated. In the present… read more here.
Keywords: 612 akt2; linc00152; akt2 pathway; glioblastoma ... See more keywords
Identification of Circulating Long Noncoding RNA Linc00152 as a Novel Biomarker for Diagnosis and Monitoring of Non-Small-Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2017 at "Disease Markers"
DOI: 10.1155/2017/7439698
Abstract: Objective Long noncoding RNAs (lncRNAs) have been reported to play vital roles in non-small-cell lung cancer (NSCLC). Recently, long noncoding RNA Linc00152 has been reported to play important roles in various cancers. In this study,… read more here.
Keywords: long noncoding; linc00152; lung cancer; cell lung ... See more keywords
Zebrafish xenograft model of human lung cancer for studying the function of LINC00152 in cell proliferation and invasion
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01460-z
Abstract: Background Numerous studies have shown that long noncoding RNAs play important roles in human cancer progression. Although zebrafish xenografts have recently become a novel in vivo model for human cancer research, whether such models can… read more here.
Keywords: linc00152; zebrafish xenograft; model; lung cancer ... See more keywords
Clinical relevance of LINC00152 and its variants in western Chinese tuberculosis patients
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.23297
Abstract: Recent studies indicate that the long intergenic non-coding RNA LINC00152 plays crucial roles in various human diseases. Here, we investigated whether levels of LINC00152 or its genetic variants correlate with the clinical features of tuberculosis… read more here.
Keywords: linc00152; clinical relevance; variants western; linc00152 variants ... See more keywords
LINC00152 promotes the growth and invasion of oral squamous cell carcinoma by regulating miR-139-5p
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s168807
Abstract: Background LINC00152 plays a crucial role in tumorigenesis and progression of multiple types of cancer. However, the biological significance of LINC00152 and its potential role in oral squamous cell carcinoma (OSCC) remain to be determined.… read more here.
Keywords: mir 139; linc00152; oral squamous; squamous cell ... See more keywords
Down-regulation of lncRNA LINC00152 Suppresses Gastric Cancer Cell Migration and Invasion Through Inhibition of the ERK/MAPK Signaling Pathway
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DOI: 10.2147/ott.s217452
Abstract: Purpose The aim of this study was to explore the regulatory role and mechanism of long noncoding RNA LINC00152 in gastric cancer (GC) cells. Methods LINC00152 expression in GC tissues and cells was detected by… read more here.
Keywords: expression; erk mapk; signaling pathway; mapk signaling ... See more keywords
Enterobacterial LPS-inducible LINC00152 is regulated by histone lactylation and promotes cancer cells invasion and migration
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.913815
Abstract: Gut microbes participate in pathogenesis by interacting with the host genome through epigenetic mechanisms, such as long non-coding RNAs. However, the mechanisms by which the microbiota induce expression alteration of long non-coding RNAs remains unclear.… read more here.
Keywords: inducible linc00152; lps inducible; expression; histone lactylation ... See more keywords
LINC00152 Promotes Tumor Progression and Predicts Poor Prognosis by Stabilizing BCL6 From Degradation in the Epithelial Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.555132
Abstract: Long non-coding RNA 00152 (LINC00152) is tumorigenic in multiple somatic malignancies. However, its prognostic significance and molecular mechanisms in the epithelial ovarian cancer (EOC) remain elusive. Here our study reveals that dysregulation of LINC00152 is… read more here.
Keywords: linc00152; epithelial ovarian; ovarian cancer; poor prognosis ... See more keywords
Long non-coding RNA LINC00152 in cancer: Roles, mechanisms, and chemotherapy and radiotherapy resistance
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DOI: 10.3389/fonc.2022.960193
Abstract: Long non-coding RNA LINC00152 (cytoskeleton regulator, or LINC00152) is an 828-bp lncRNA located on chromosome 2p11.2. LINC00152 was originally discovered during research on hepatocarcinogenesis and has since been regarded as a crucial oncogene that regulates… read more here.
Keywords: chemotherapy radiotherapy; linc00152; cancer; radiotherapy resistance ... See more keywords
Long non-coding RNA LINC00152/miR-613/CD164 axis regulates cell proliferation, apoptosis, migration and invasion in glioma via PI3K/AKT pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Neoplasma"
DOI: 10.4149/neo_2020_190706n598
Abstract: Malignant glioma is the most frequent primary brain tumor in adults. Accumulated evidence showed that long non-coding RNA (lncRNA) long intergenic noncoding RNA 152 (LINC00152) participated in the progression of glioma, while the regulatory mechanisms… read more here.
Keywords: glioma; mir 613; cd164; migration invasion ... See more keywords