Overexpression of LINC00261 inhibits non–small cell lung cancer cells progression by interacting with miR‐522‐3p and suppressing Wnt signaling
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DOI: 10.1002/jcb.29149
Abstract: Long noncoding RNA LINC00261 has been experimentally validated to function as a tumor suppressor in several cancers, but its pathological role and functional mechanism in non–small cell lung cancer (NSCLC) are largely unclear. In this… read more here.
Keywords: overexpression; wnt signaling; linc00261; cancer ... See more keywords
Long non-coding RNA LINC00261 sensitizes human colon cancer cells to cisplatin therapy
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20176793
Abstract: Colon cancer is one of the most common digestive tumors. The present study aimed to explore the functional role, as well as the underlying mechanism of long non-coding RNA LINC00261 in colon cancer. Expression of… read more here.
Keywords: colon; colon cancer; linc00261; cancer cells ... See more keywords
LINC00261 Is Differentially Expressed in Pancreatic Cancer Subtypes and Regulates a Pro-Epithelial Cell Identity
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DOI: 10.3390/cancers12051227
Abstract: Pancreatic adenocarcinoma (PDAC) is one of the major causes of cancer-associated deaths worldwide, with a dismal prognosis that has not significantly changed over the last decades. Transcriptional analysis has provided valuable insights into pancreatic tumorigenesis.… read more here.
Keywords: pdac; pancreatic cancer; pro epithelial; linc00261 ... See more keywords
Long Noncoding RNA LINC00261 Suppresses Cell Proliferation and Invasion and Promotes Cell Apoptosis in Human Choriocarcinoma
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DOI: 10.3727/096504016x14772362173376
Abstract: Choriocarcinoma is one of the gestational trophoblastic neoplasias (GTNs) that originate in the chorionic villi and the extravillous trophoblast. Long noncoding RNAs (lncRNAs) are a type of non-protein-coding RNAs that have recently been implicated in… read more here.
Keywords: choriocarcinoma; apoptosis; cell proliferation; linc00261 ... See more keywords
Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription
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DOI: 10.7150/thno.44278
Abstract: Background: Due to the limitations of strategies for its early diagnosis and treatment, pancreatic cancer (PC) remains a substantial human health threat. We previously discovered a methylation-mediated lncRNA, LINC00261, which is downregulated in PC tissues.… read more here.
Keywords: myc transcription; methylation; mediated linc00261; pancreatic cancer ... See more keywords