Articles with "linc00261" as a keyword



Overexpression of LINC00261 inhibits non–small cell lung cancer cells progression by interacting with miR‐522‐3p and suppressing Wnt signaling

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.29149

Abstract: Long noncoding RNA LINC00261 has been experimentally validated to function as a tumor suppressor in several cancers, but its pathological role and functional mechanism in non–small cell lung cancer (NSCLC) are largely unclear. In this… read more here.

Keywords: overexpression; wnt signaling; linc00261; cancer ... See more keywords

Abstract 180: LINC00261 is functionally linked to tumor DNA mutational burden and tumor immune microenvironment composition in lung adenocarcinoma

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-180

Abstract: Immunotherapy has emerged as a breakthrough in the improvement of survival outcomes for lung adenocarcinoma (LUAD), however effective response requires the combination of blocking inhibitory signals on the tumor surface and antigen presentation to the… read more here.

Keywords: cancer; lung adenocarcinoma; tumor; linc00261 ... See more keywords

Abstract A016: LINC00261 is functionally linked to tumor DNA mutational burden and tumor immune microenvironment composition in lung adenocarcinoma

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.dnarepair24-a016

Abstract: Immunotherapy has emerged as a breakthrough in the improvement of survival outcomes for lung adenocarcinoma (LUAD), however effective response requires the combination of blocking inhibitory signals on the tumor surface and antigen presentation to the… read more here.

Keywords: cancer; lung adenocarcinoma; tumor; linc00261 ... See more keywords

Long non-coding RNA LINC00261 sensitizes human colon cancer cells to cisplatin therapy

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Published in 2017 at "Brazilian Journal of Medical and Biological Research"

DOI: 10.1590/1414-431x20176793

Abstract: Colon cancer is one of the most common digestive tumors. The present study aimed to explore the functional role, as well as the underlying mechanism of long non-coding RNA LINC00261 in colon cancer. Expression of… read more here.

Keywords: colon; colon cancer; linc00261; cancer cells ... See more keywords

LINC00261 Is Differentially Expressed in Pancreatic Cancer Subtypes and Regulates a Pro-Epithelial Cell Identity

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Published in 2020 at "Cancers"

DOI: 10.3390/cancers12051227

Abstract: Pancreatic adenocarcinoma (PDAC) is one of the major causes of cancer-associated deaths worldwide, with a dismal prognosis that has not significantly changed over the last decades. Transcriptional analysis has provided valuable insights into pancreatic tumorigenesis.… read more here.

Keywords: pdac; pancreatic cancer; pro epithelial; linc00261 ... See more keywords

Long Noncoding RNA LINC00261 Suppresses Cell Proliferation and Invasion and Promotes Cell Apoptosis in Human Choriocarcinoma

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Published in 2017 at "Oncology Research"

DOI: 10.3727/096504016x14772362173376

Abstract: Choriocarcinoma is one of the gestational trophoblastic neoplasias (GTNs) that originate in the chorionic villi and the extravillous trophoblast. Long noncoding RNAs (lncRNAs) are a type of non-protein-coding RNAs that have recently been implicated in… read more here.

Keywords: choriocarcinoma; apoptosis; cell proliferation; linc00261 ... See more keywords

Methylation-mediated LINC00261 suppresses pancreatic cancer progression by epigenetically inhibiting c-Myc transcription

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Published in 2020 at "Theranostics"

DOI: 10.7150/thno.44278

Abstract: Background: Due to the limitations of strategies for its early diagnosis and treatment, pancreatic cancer (PC) remains a substantial human health threat. We previously discovered a methylation-mediated lncRNA, LINC00261, which is downregulated in PC tissues.… read more here.

Keywords: myc transcription; methylation; mediated linc00261; pancreatic cancer ... See more keywords