Generation of a laminopathies-specific iPSC line EHTJUi005-A-3 with homozygous knockout of the LMNA gene by CRISPR/Cas9 technology.
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DOI: 10.1016/j.scr.2021.102530
Abstract: LAMIN A/C, encoded by the LMNA gene, supports the normal structure of the cell nucleus and regulates the connection between the nucleus and the cytoskeleton as a component of the nucleus envelope. The loss of… read more here.
Keywords: line ehtjui005; ehtjui005 homozygous; lmna gene; gene ... See more keywords