Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cell research"
DOI: 10.1016/j.scr.2021.102522
Abstract: MNX1 encodes a homeobox transcription factor with conserved embryonic requirements in spinal motor neuron formation and pancreatic beta-cell differentiation. Mutations in MNX1 are associated with dominantly inherited Currarino syndrome and neonatal diabetes. To better understand… read more here.
Keywords: line expressing; line; generation hipsc; mnx1 ... See more keywords
Characterization of a Knock-In Mouse Line Expressing a Fusion Protein of κ Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging via CLARITY
Sign Up to like & getrecommendations! Published in 2020 at "eNeuro"
DOI: 10.1523/eneuro.0028-20.2020
Abstract: Abstract Activation of κ opioid receptor (KOR) produces analgesia, antipruritic effect, sedation and dysphoria. To characterize neuroanatomy of KOR at high resolutions and circumvent issues of specificity of KOR antibodies, we generated a knock-in mouse… read more here.
Keywords: mouse line; opioid receptor; line expressing; brain ... See more keywords