Trends in utilization of first‐line palliative treatments for anal squamous cell carcinoma
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DOI: 10.1002/cam4.5126
Abstract: Anal squamous cell carcinoma patients often present with significant symptoms, including pain, bleeding, and obstructive symptoms. This requires palliation‐directed therapy as a first‐line treatment to alleviate symptoms. The proportion of patients receiving first‐line palliative treatments… read more here.
Keywords: cell carcinoma; anal squamous; line palliative; squamous cell ... See more keywords
KRASG12C/TP53 co-mutations identify long-term responders to first line palliative treatment with pembrolizumab monotherapy in PD-L1 high (≥50%) lung adenocarcinoma.
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DOI: 10.21037/tlcr-20-958
Abstract: Background Pembrolizumab is a standard of care as first line palliative therapy in PD-L1 overexpressing (≥50%) non-small cell lung cancer (NSCLC). This study aimed at the identification of KRAS and TP53-defined mutational subgroups in the… read more here.
Keywords: first line; long term; term responders; tp53 mutations ... See more keywords
Real World Evidence on Second-Line Palliative Chemotherapy in Advanced Pancreatic Cancer
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DOI: 10.3389/fonc.2020.01176
Abstract: Background: The outcome and tolerability of palliative second line chemotherapy for advanced pancreatic cancer (APC) in real life patients are largely unknown. Prognostic parameters for risk stratification and treatment guidance are lacking. Materials and Methods:… read more here.
Keywords: line; palliative chemotherapy; cancer; line palliative ... See more keywords