GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2100751118
Abstract: Significance Assembly-line polyketide synthases (PKSs) make many medicinally significant natural products. A better understanding of evolutionary mechanisms underlying polyketide diversification could open new avenues for PKS engineering and drug discovery. In the course of interrogating… read more here.
Keywords: line; diversification; line polyketide; polyketide synthases ... See more keywords