A multiauxotrophic CHO cell line for the rapid isolation of producers of diverse or high levels of recombinant proteins
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DOI: 10.1002/bit.28074
Abstract: Chinese Hamster Ovary (CHO) cells are widely used for the high‐level production of recombinant proteins. We created a multiauxotrophic mutant of CHO‐K1 cells, CHO8A, that is deficient in eight enzymatic steps in the purine/pyrimidine biosynthetic… read more here.
Keywords: cell; line rapid; recombinant proteins; cho cell ... See more keywords