Synthesis and Characterization of Specific Reverse Transcriptase Inhibitors for Mammalian LINE-1 Retrotransposons.
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DOI: 10.1016/j.chembiol.2019.04.010
Abstract: Retrotransposons are a type of transposable element (TE) that have amplified to astonishing numbers in mammalian genomes, comprising more than a third of the human and mouse genomes. Long interspersed element class 1 (LINE-1 or… read more here.
Keywords: line; transcriptase inhibitors; line retrotransposons; mammalian line ... See more keywords