Assessment of First-line Therapy With Midazolam for Prehospital Seizures in Children
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.6990
Abstract: This cohort study assesses the effectiveness of midazolam treatment in terminating pediatric seizures in the prehospital setting. read more here.
Keywords: midazolam prehospital; line therapy; midazolam; first line ... See more keywords
Third‐line therapy for overactive bladder in the elderly: Nuances and considerations
Sign Up to like & getrecommendations! Published in 2022 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24965
Abstract: Overactive bladder (OAB) disproportionally affects older adults in both incidence and severity. OAB pharmacotherapy is often problematic in the elderly due to polypharmacy, adverse side effect profiles and contraindications in the setting of multiple comorbidities,… read more here.
Keywords: third line; line therapy; overactive bladder;
An analysis of factors that influence patient preference of third‐line therapy for overactive bladder
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DOI: 10.1002/nau.25046
Abstract: Patients with overactive bladder (OAB) refractory to first‐ and second‐line therapy may pursue third‐line therapies, including intradetrusor onabotulinum toxin‐A (BTX), peripheral tibial nerve stimulation (PTNS), and sacral neuromodulation (SNM). The factors that influence patient preference… read more here.
Keywords: line therapy; third line; factors influence; overactive bladder ... See more keywords
A randomized phase II trial of erlotinib vs. S-1 as a third- or fourth-line therapy for patients with wild-type EGFR non-small cell lung cancer (HOT1002)
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3432-4
Abstract: PurposeA high proportion of patients with wild-type EGFR non-small cell lung cancer (NSCLC) receive third-line therapy and beyond, with no prospective randomized trials addressing the issue. This study aimed to select the most suitable regimen… read more here.
Keywords: type egfr; wild type; line therapy;
Ramucirumab as a second line therapy for advanced HCC: a significant achievement or a wasted opportunity for personalised therapy?
Sign Up to like & getrecommendations! Published in 2019 at "Investigational New Drugs"
DOI: 10.1007/s10637-019-00760-0
Abstract: SummaryThe second line treatment of hepatocellular carcinoma (HCC) has recently become an exciting area of interest since new emerging options have demonstrated survival benefits versus placebo. Unfortunately, predictive biomarkers are unavailable for these treatments. Ramucirumab,… read more here.
Keywords: advanced hcc; therapy advanced; therapy; line therapy ... See more keywords
Efficacy of Docetaxel and Oxaliplatin Regimen as a Second-Line Therapy for Patients with Advanced Pancreatic Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Gastrointestinal Cancer"
DOI: 10.1007/s12029-018-0116-1
Abstract: Background and Aim of WorkPancreatic cancer is the deadliest of the 21 most common cancers, largely because it is often identified at a late stage, we aimed to determine the control rates, and PFS for… read more here.
Keywords: line; oxaliplatin regimen; docetaxel oxaliplatin; therapy patients ... See more keywords
Real-World Data Analysis of Second-Line Antiangiogenic Targeted Treatments Following Anti-Epidermal Growth Factor Receptor Monoclonal Antibodies and First-Line FOLFOX for Patients with Metastatic Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Advances in Therapy"
DOI: 10.1007/s12325-022-02122-4
Abstract: Evidence is lacking on second-line and later treatments for patients with RAS wild-type colorectal cancer (CRC) who receive first-line anti-epidermal growth factor receptor (EGFR) antibody therapy. In this study, we explored the real-world treatment sequences,… read more here.
Keywords: treatment; second line; line therapy; line ... See more keywords
15: Identifying barriers to third‐line therapy: a patient‐centered approach to refractory overactive bladder
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2019.01.044
Abstract: 15 Identifying barriers to third-line therapy: a patient-centered approach to refractory overactive bladder A. Davenport, S. Stark, A. Quian, D. Sheyn, J. Mangel Case Western Reserve University, Cleveland, OH, Obstetrics & Gynecology, MetroHealth Medical Center,… read more here.
Keywords: medicine; third line; therapy; refractory ... See more keywords
Increasing Options for First-Line Therapy in Primary FSGS?
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DOI: 10.1016/j.ekir.2018.10.016
Abstract: F ocal segmental glomerulosclerosis (FSGS) is a common pathologic diagnosis on kidney biopsy. It denotes focal and segmental intracapillary hyaline deposition and/or focal adhesions of capillaries to Bowman’s capsule. When it occurs without underlying alternate… read more here.
Keywords: options first; therapy; first line; increasing options ... See more keywords
Severe adverse events impact overall survival and costs in elderly patients with advanced non-small cell lung cancer on second-line therapy.
Sign Up to like & getrecommendations! Published in 2018 at "Lung cancer"
DOI: 10.1016/j.lungcan.2018.02.011
Abstract: OBJECTIVES Elderly patients with advanced non-small lung cancer (aNSCLC) represent a high-risk patient population due to disease burden, comorbidities, and performance status, particularly after progressing on first-line therapy. Among elderly patients who receive second-line therapy,… read more here.
Keywords: line; severe aes; elderly patients; line therapy ... See more keywords
IL-1 blockers together with colchicine may be administered as first line therapy in familial Mediterranean fever with amyloidosis.
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DOI: 10.1016/j.mehy.2019.109269
Abstract: Colchicine is the first choice of the treatment in familial Mediterranean fever (FMF). However, in FMF patients with amyloidosis, especially during creatinine level >1.5 mg/dL and nephrotic range proteinuria, colchicine may be ineffective. Interleukin-1 (IL-1) blockers… read more here.
Keywords: colchicine may; together colchicine; familial mediterranean; line therapy ... See more keywords