Photoactive Interfaces for Spatio-Temporal Guidance of Mesenchymal Stem Cell Fate.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202000470
Abstract: Patterned surfaces have proved effective in guiding stem cells commitment to a specific lineage by presenting highly ordered biophysical/biochemical cues at the cellmaterial interface. Their potency in controlling cell fate can be significantly empowered by… read more here.
Keywords: photoactive interfaces; lineage; cell fate; stem ... See more keywords
Assessing Biomaterial‐Induced Stem Cell Lineage Fate by Machine Learning‐Based Artificial Intelligence
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210637
Abstract: Current functional assessment of biomaterial‐induced stem cell lineage fate in vitro mainly relies on biomarker‐dependent methods with limited accuracy and efficiency. Here a “Mesenchymal stem cell Differentiation Prediction (MeD‐P)” framework for biomaterial‐induced cell lineage fate… read more here.
Keywords: lineage fate; stem cell; lineage;
Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104682
Abstract: Direct cell reprogramming, also called transdifferentiation, is valuable for cell fate studies and regenerative medicine. Current approaches to transdifferentiation are usually achieved by directly targeting the nuclear functions, such as manipulating the lineage‐specific transcriptional factors,… read more here.
Keywords: cell; pharmacological perturbation; transdifferentiation; fibroblasts neurons ... See more keywords
Creating Lineage Trajectory Maps Via Integration of Single‐Cell RNA‐Sequencing and Lineage Tracing
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DOI: 10.1002/bies.201800056
Abstract: Mapping the paths that stem and progenitor cells take en route to differentiate and elucidating the underlying molecular controls are key goals in developmental and stem cell biology. However, with population level analyses it is… read more here.
Keywords: single cell; lineage trajectory; lineage; cell rna ... See more keywords
Signaling pathways in mammalian preimplantation development: Linking cellular phenotypes to lineage decisions
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DOI: 10.1002/dvdy.24471
Abstract: The first stages of mammalian development, before implantation of the embryo in the maternal uterus, result in the establishment of three cell populations in the blastocyst: trophectoderm, epiblast, and primitive endoderm. These events involve only… read more here.
Keywords: signaling pathways; lineage; pathways mammalian; cellular phenotypes ... See more keywords
PDGFRα lineage origin directs monocytes to trafficking proficiency to support peripheral immunity.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of immunology"
DOI: 10.1002/eji.202149479
Abstract: Multiple embryonic precursors give rise to leukocytes in adult while the lineage-based functional impacts are underappreciated. Mesodermal precursors expressing PDGFRα appear transiently during E7.5-8.5 descend to a subset of Lin- Sca1+ Kit+ hematopoietic progenitors found… read more here.
Keywords: lineage; support peripheral; lineage origin; pdgfr lineage ... See more keywords
TCF7l2, a nuclear marker that labels premyelinating oligodendrocytes and promotes oligodendroglial lineage progression
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DOI: 10.1002/glia.24249
Abstract: Clinical and basic neuroscience research is greatly benefited from the identification and characterization of lineage specific and developmental stage‐specific markers. In the glial research community, histological markers that specifically label newly differentiated premyelinating oligodendrocytes are… read more here.
Keywords: premyelinating oligodendrocytes; oligodendroglial lineage; lineage; tcf7l2 ... See more keywords
Technical approaches and challenges to study AMPA receptors in oligodendrocyte lineage cells: Past, present, and future
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24305
Abstract: Receptors for α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid (AMPARs) are ligand‐gated ionotropic receptors for glutamate that is a major excitatory neurotransmitter in the central nervous system. AMPARs are located at postsynaptic sites of neuronal synapses where they mediate fast… read more here.
Keywords: oligodendrocyte lineage; technical approaches; lineage cells; lineage ... See more keywords
Parathyroid Hormone Shifts Cell Fate of a Leptin Receptor‐Marked Stromal Population from Adipogenic to Osteoblastic Lineage
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3811
Abstract: Intermittent parathyroid hormone (iPTH) treatment induces bone anabolic effects that result in the recovery of osteoporotic bone loss. Human PTH is usually given to osteoporotic patients because it induces osteoblastogenesis. However, the mechanism by which… read more here.
Keywords: lineage; parathyroid hormone; treatment; bone ... See more keywords
VP7 and VP4 genotypes of rotaviruses cocirculating in Iran, 2015 to 2017: Comparison with cogent sequences of Rotarix and RotaTeq vaccine strains before their use for universal mass vaccination
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25642
Abstract: The present study was conducted to analyze the genotypic diversity of circulating species A rotavirus (RVA) strains in Iran and also to investigate comparative analysis between the genotypes of VP4 and VP7 of cocirculating RVA… read more here.
Keywords: vaccine strains; lineage; iran; rotateq vaccine ... See more keywords
Genomic analysis reveals a rapid spread and predominance of lambda (C.37) SARS‐COV‐2 lineage in Peru despite circulation of variants of concern
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27261
Abstract: The pandemic generated by SARS‐Cov‐2 has caused a large number of cases and deaths in the world, but South America has been one of the continents that were most hard hit. The appearance of new… read more here.
Keywords: lambda; lineage; variants concern; concern ... See more keywords