Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming
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DOI: 10.1016/j.celrep.2018.07.077
Abstract: Summary Epiblast cells in the early post-implantation stage mammalian embryo undergo a transition described as lineage priming before cell fate allocation, but signaling pathways acting upstream remain ill defined. Genetic studies demonstrate that Smad2/3 double-mutant… read more here.
Keywords: embryonic cell; extra embryonic; lineage priming; embryonic extra ... See more keywords