Cell lineage tracing in the retina: Could material transfer distort conclusions?
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24535
Abstract: Recent studies reported the transfer of fluorescent labels between grafted and host cells after transplantation of photoreceptor precursor cells in the mouse retina. While clearly impacting the interpretation of transplantation studies in the retina, the… read more here.
Keywords: tracing retina; cell lineage; retina could; lineage tracing ... See more keywords
Pericyte Ontogeny: The Use of Chimeras to Track a Cell Lineage of Diverse Germ Line Origins.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1056-5_6
Abstract: The goal of lineage tracing is to understand body formation over time by discovering which cells are the progeny of a specific, identified, ancestral progenitor. Subsidiary questions include unequivocal identification of what they have become,… read more here.
Keywords: ontogeny use; lineage; pericyte ontogeny; lineage tracing ... See more keywords
Application of Cell Lineage Tracing Combined with Immunofluorescence in the Study of Dentinogenesis.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9012-2_5
Abstract: The cell lineage tracing system has been used predominantly in developmental biology studies. The Cre recombinase allows for the activation of the reporter in a specific cell line and all progeny. In this protocol, we… read more here.
Keywords: cell lineage; lineage tracing; immunofluorescence; biology ... See more keywords
Methods for lineage tracing on the organism-wide level.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2017.11.004
Abstract: Determining the lineage origin of cell types is a major goal in developmental biology. Furthermore, lineage tracing is a powerful approach for understanding the origin of developmental defects as well as the origin of diseases… read more here.
Keywords: organism wide; lineage tracing; wide level; biology ... See more keywords
Lineage commitment of hematopoietic stem cells and progenitors: insights from recent single cell and lineage tracing technologies.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental hematology"
DOI: 10.1016/j.exphem.2020.07.002
Abstract: Blood production is essential to maintain human health, and even small perturbations in hematopoiesis can cause disease. Hematopoiesis has therefore been the focus of much research for many years. Experiments determining the lineage potentials of… read more here.
Keywords: single cell; lineage; lineage commitment; lineage tracing ... See more keywords
Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells.
Sign Up to like & getrecommendations! Published in 2022 at "Immunity"
DOI: 10.1016/j.immuni.2022.01.016
Abstract: Developmental origins of dendritic cells (DCs) including conventional DCs (cDCs, comprising cDC1 and cDC2 subsets) and plasmacytoid DCs (pDCs) remain unclear. We studied DC development in unmanipulated adult mice using inducible lineage tracing combined with… read more here.
Keywords: pdcs; clonal lineage; shared origin; dendritic cells ... See more keywords
Cell lineage tracing revealed the reversion of liver tumor cells to normal hepatocytes during tumor regression of xmrk transgenic zebrafish
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.036
Abstract: Our group has previously established several inducible hepatocellular carcinoma (HCC) models in zebrafish by transgenic expression of selected oncogenes. One common and important feature of these liver tumor models is the reversibility of tumor after… read more here.
Keywords: tumor cells; lineage tracing; expression; xmrk ... See more keywords
Lineage tracing of sclerotome cells in amphibian reveals that multipotent somitic cells originate from lateral somitic frontier.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental biology"
DOI: 10.1016/j.ydbio.2019.05.009
Abstract: The two somite compartments, dorso-lateral dermomyotome and medio-ventral sclerotome are major vertebrate novelties, but little is known about their evolutionary origin. We determined that sclerotome cells in Xenopus come from lateral somitic frontier (LSF) by… read more here.
Keywords: somitic frontier; multipotent somitic; somitic cells; sclerotome cells ... See more keywords
Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14284
Abstract: Androgen signals through androgen receptor (AR) to influence prostate development and cancer. How stromal and epithelial AR regulate prostate homeostasis remains unclear. Using genetic lineage tracing, we systematically investigated the role of cell-autonomous AR in… read more here.
Keywords: prostate; cell; prostate homeostasis; lineage tracing ... See more keywords
Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09203-z
Abstract: Determining cell lineage and function is critical to understanding human physiology and pathology. Although advances in lineage tracing methods provide new insight into cell fate, defining cellular diversity at the mammalian level remains a challenge.… read more here.
Keywords: tracing using; system; lineage tracing; cell ... See more keywords
In vivo lineage tracing in mice
Sign Up to like & getrecommendations! Published in 2018 at "Nature Reviews Genetics"
DOI: 10.1038/s41576-018-0048-4
Abstract: A study in Science reports the successful application of CRISPR–Cas genome editing to track and reconstruct developmental lineages in the mouse. read more here.
Keywords: tracing mice; lineage tracing; vivo lineage;