Linear and Convergent Syntheses of Bifunctional Hydroxy-Bisphosphonic Compounds as Potential Bone-Targeting Prodrugs
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DOI: 10.1055/s-0037-1611540
Abstract: The synthesis of two bifunctional compounds bearing a terminal hydroxy-bisphosphonic function (HBP) was achieved following a linear and a convergent strategy. In the linear approach, the free hydroxy-bisphosphonic function was introduced in the last step… read more here.
Keywords: convergent syntheses; hydroxy bisphosphonic; syntheses bifunctional; bone targeting ... See more keywords