Articles with "lines dlst" as a keyword



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Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels

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Published in 2023 at "Oncotarget"

DOI: 10.18632/oncotarget.28342

Abstract: Overexpression of the dihydrolipoamide S-succinyltransferase (DLST) is associated with poor outcome in neuroblastoma patients and triple-negative breast cancer (TNBC) and specifically with the oxidative phosphorylation (OXPHOS) pathway. Inhibitors of OXPHOS were previously suggested as a… read more here.

Keywords: cell; lines dlst; mrna levels; high mrna ... See more keywords