Linezolid as treatment for pulmonary Mycobacterium avium disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx304
Abstract: Objectives To identify the pharmacokinetic/pharmacodynamic parameters and exposures of linezolid in the treatment of pulmonary Mycobacterium avium complex (MAC) disease. Methods Human-derived monocytes infected with MAC were inoculated into hollow-fibre systems for dose-effect and dose-scheduling… read more here.
Keywords: treatment pulmonary; pulmonary mycobacterium; linezolid treatment; mycobacterium avium ... See more keywords
Linezolid for the treatment of postneurosurgical infection caused by methicillin-resistant Staphylococcus
Sign Up to like & getrecommendations! Published in 2019 at "Surgical Neurology International"
DOI: 10.25259/sni_455_2019
Abstract: Background: Postneurosurgical infection (PNSI) is a major problem. Linezolid is a bacteriostatic oxazolidinone antibiotic with a highly activity against Gram-positive cocci resistant to methicillin and a good cerebrospinal fluid penetration. The purpose of this study… read more here.
Keywords: linezolid treatment; staphylococcus; infection; postneurosurgical infection ... See more keywords
Population pharmacokinetics and dose evaluations of linezolid in the treatment of multidrug-resistant tuberculosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1032674
Abstract: Background: The pharmacokinetic/pharmacodynamics (PK/PD) target derived from the hollow-fiber system model for linezolid for treatment of the multidrug-resistant tuberculosis (MDR-TB) requires clinical validation. Therefore, this study aimed to develop a population PK model for linezolid… read more here.
Keywords: linezolid treatment; treatment multidrug; population; model ... See more keywords