GW29-e0366 An Exploration of Therapeutic Mechanism of Lingguizhugan Decoction in Chronic Heart Failure Based on Network Pharmacology
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.052
Abstract: Lingguizhugan decoction (LGZGD), a well-known traditional Chinese medicine (TCM) formula has been widely using in modern clinical practice to treat various cardiovascular disease, especially in chronic heart failure (CHF). However, the underlying therapeutic mechanism is not… read more here.
Keywords: therapeutic mechanism; heart failure; pharmacology; lingguizhugan decoction ... See more keywords
Lingguizhugan decoction improves non-alcoholic fatty liver disease by altering insulin resistance and lipid metabolism related genes: a whole trancriptome study by RNA-Seq
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19734
Abstract: Lingguizhugan decoction, a classic traditional Chinese medicine formula, has been used to treat non-alcoholic fatty liver disease (NAFLD), however, the underlying mechanisms remains unclear. In the present study, we compared the phenotype of the normal… read more here.
Keywords: alcoholic fatty; decoction; fatty liver; non alcoholic ... See more keywords
Lingguizhugan Decoction Targets Intestinal Microbiota and Metabolites to Reduce Insulin Resistance in High-Fat Diet Rats
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy"
DOI: 10.2147/dmso.s370492
Abstract: Background The increasing incidence of obesity and its complications has become a global public health problem. Lingguizhugan decoction (LGZGD) is a representative compound of traditional Chinese medicine (TCM) for metabolic diseases, such as nonalcoholic fatty… read more here.
Keywords: microbiota; microbiota metabolites; insulin resistance; high fat ... See more keywords
Lingguizhugan decoction improves non-alcoholic steatohepatitis partially by modulating gut microbiota and correlated metabolites
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2023.1066053
Abstract: Background Lingguizhugan decoction is a traditional Chinese medicine prescription that has been used to improve non-alcoholic fatty liver disease and its progressive form, non-alcoholic steatohepatitis (NASH). However, the anti-NASH effects and underlying mechanisms of Lingguizhugan… read more here.
Keywords: decoction; alcoholic steatohepatitis; non alcoholic; gut microbiota ... See more keywords