The missing link: allostery and catalysis in the anti-viral protein SAMHD1
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DOI: 10.1042/bst20180348
Abstract: Vertebrate protein SAMHD1 (sterile-α-motif and HD domain containing protein 1) regulates the cellular dNTP (2′-deoxynucleoside-5′-triphosphate) pool by catalysing the hydrolysis of dNTP into 2′-deoxynucleoside and triphosphate products. As an important regulator of cell proliferation and… read more here.
Keywords: link allostery; samhd1; protein samhd1; missing link ... See more keywords