Articles with "linkage analysis" as a keyword



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Model-Based Linkage Analysis of a Quantitative Trait.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7274-6_14

Abstract: Linkage Analysis is a family-based method of analysis to examine whether any typed genetic markers cosegregate with a given trait, in this case a quantitative trait. If linkage exists, this is taken as evidence in… read more here.

Keywords: analysis; linkage analysis; model; quantitative trait ... See more keywords
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Model-Based Linkage Analysis of a Binary Trait.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7274-6_15

Abstract: Linkage analysis is a statistical genetics method to localize disease and trait genes to specific chromosome regions. The analysis requires pedigrees with members who vary among each other in the trait of interest and who… read more here.

Keywords: binary trait; analysis; linkage analysis; model ... See more keywords
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Model-Free Linkage Analysis of a Quantitative Trait.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7274-6_16

Abstract: Model-free methods of linkage analysis for quantitative traits are a class of easily implemented, computationally efficient and statistically robust approaches to searching for linkage to a quantitative trait. By "model-free" we refer to methods of… read more here.

Keywords: analysis quantitative; analysis; linkage analysis; model ... See more keywords
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Genetic dissection of wheat panicle traits using linkage analysis and a genome-wide association study

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Published in 2018 at "Theoretical and Applied Genetics"

DOI: 10.1007/s00122-018-3059-9

Abstract: Key messageCoincident regions on chromosome 4B for GW, on 5A for SD and TSS, and on 3A for SL and GNS were detected through an integration of a linkage analysis and a genome-wide association study… read more here.

Keywords: genome wide; wheat; analysis; linkage analysis ... See more keywords
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Identification of QTL and genes for pod number in soybean by linkage analysis and genome-wide association studies

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Published in 2020 at "Molecular Breeding"

DOI: 10.1007/s11032-020-01140-w

Abstract: Pod number is an important component of yield in soybean ( Glycine max (L.) Merr.), and pods are unevenly distributed in the upper, middle and lower parts of the plant. Here, linkage analysis combined with… read more here.

Keywords: genome wide; pod number; linkage analysis; number ... See more keywords
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SA24 COMBINED WHOLE EXOME SEQUENCING AND LINKAGE ANALYSIS REVEALS LINKAGE TO 10Q11-10Q21 LOCUS WHICH IS NOT EXPLAINED BY GWAS-ASSOCIATED SNP OR RARE VARIANTS IN ANK3

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Published in 2019 at "European Neuropsychopharmacology"

DOI: 10.1016/j.euroneuro.2017.08.096

Abstract: Background Bipolar Disorder (BD) is a common, complex psychiatric condition characterized by recurrent fluctuations of mood. Historically, linkage approaches implicated a number of genetic loci, but signals typically failed to be replicated due to heterogeneity… read more here.

Keywords: exome sequencing; analysis; linkage analysis; linkage ... See more keywords
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A high-dimensional linkage analysis model for characterizing crossover interference

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Published in 2017 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbw033

Abstract: Linkage analysis has played an important role in understanding genome structure and evolution. However, two-point linkage analysis widely used for genetic map construction can rarely chart a detailed picture of genome organization because it fails… read more here.

Keywords: analysis; linkage analysis; crossover interference; point ... See more keywords
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AlloMap6: an R package for genetic linkage analysis in allohexaploids

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Published in 2017 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbw085

Abstract: Allopolyploids are a group of polyploids with more than two sets of chromosomes derived from different species. Previous linkage analysis of allopolyploids is based on the assumption that different chromosomes pair randomly during meiosis. A… read more here.

Keywords: analysis; linkage analysis; preferential pairing; allomap6 package ... See more keywords
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polymapR—linkage analysis and genetic map construction from F1 populations of outcrossing polyploids

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Published in 2019 at "Bioinformatics"

DOI: 10.1093/bioinformatics/bty1002

Abstract: In the original article, there was an incorrect formula. The formula appears in section 2.2.2, 'Linkage analysis in the presence of preferential chromosomal pairing', on page 3498. The correct formula is below in the context… read more here.

Keywords: analysis genetic; linkage analysis; polymapr linkage; formula ... See more keywords
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Integration of GWAS, linkage analysis and transcriptome analysis to reveal the genetic basis of flowering time-related traits in maize

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Published in 2023 at "Frontiers in Plant Science"

DOI: 10.3389/fpls.2023.1145327

Abstract: Maize (Zea mays) inbred lines vary greatly in flowering time, but the genetic basis of this variation is unknown. In this study, three maize flowering-related traits (DTT, days to tasselling; DTP, days to pollen shed;… read more here.

Keywords: linkage analysis; analysis; flowering time; transcriptome analysis ... See more keywords