Articles with "linkage studies" as a keyword



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The long and winding road: From mouse linkage studies to a novel human therapeutic pathway in type 1 diabetes

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.918837

Abstract: Autoimmunity involves a loss of immune tolerance to self-proteins due to a combination of genetic susceptibility and environmental provocation, which generates autoreactive T and B cells. Genetic susceptibility affects lymphocyte autoreactivity at the level of… read more here.

Keywords: linkage studies; autoimmunity; susceptibility; tolerance ... See more keywords