Is Methamphetamine-Linked Cardiomyopathy an Emerging Epidemic for New Generation?
Sign Up to like & getrecommendations! Published in 2021 at "Current problems in cardiology"
DOI: 10.1016/j.cpcardiol.2021.101042
Abstract: The use of methamphetamines is growing worldwide with cardiovascular disease as the leading cause of mortality and morbidity. Long-term use of methamphetamines is associated with malignant hypertension, myocardial ischemia, pulmonary hypertension, and methamphetamines-associated cardiomyopathy. These… read more here.
Keywords: new generation; epidemic new; cardiomyopathy emerging; emerging epidemic ... See more keywords
A recessive mutation in the DSP gene linked to cardiomyopathy, skin fragility and hair defects impairs the binding of desmoplakin to epidermal keratins and the muscle‐specific intermediate filament desmin
Sign Up to like & getrecommendations! Published in 2018 at "British Journal of Dermatology"
DOI: 10.1111/bjd.16832
Abstract: Desmoplakin (DSP) is a cytolinker of the plakin family. It mediates the connection of intermediate filaments (IFs) to desmosomes, intercellular adhesion junctions. The carboxyl (C)-terminal tail of DSP binds to IFs, while its amino-terminal part… read more here.
Keywords: gene linked; recessive mutation; linked cardiomyopathy; mutation dsp ... See more keywords
Application of Patient-Specific iPSCs for Modelling and Treatment of X-Linked Cardiomyopathies
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DOI: 10.3390/ijms22158132
Abstract: Inherited cardiomyopathies are among the major causes of heart failure and associated with significant mortality and morbidity. Currently, over 70 genes have been linked to the etiology of various forms of cardiomyopathy, some of which… read more here.
Keywords: linked cardiomyopathies; patient specific; application patient; linked cardiomyopathy ... See more keywords