Structure of UBE2K–Ub/E3/polyUb reveals mechanisms of K48-linked Ub chain extension
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DOI: 10.1038/s41589-021-00952-x
Abstract: Ubiquitin (Ub) chain types govern distinct biological processes. K48-linked polyUb chains target substrates for proteasomal degradation, but the mechanism of Ub chain synthesis remains elusive due to the transient nature of Ub handover. Here, we… read more here.
Keywords: chain; k48 linked; linked chain; structure ... See more keywords