An adult case of X‐linked chronic granulomatous disease with skin ulcer on the nose and internal canthus
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.16291
Abstract: Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disease in which phagocytes are unable to produce reactive oxygen species (ROS) due to an impaired NADPH oxidase complex. Beginning in infancy, patients suffer recurrent infections,… read more here.
Keywords: granulomatous disease; chronic granulomatous; linked chronic; case linked ... See more keywords
Lentiviral Gene Therapy for X-Linked Chronic Granulomatous Disease
Sign Up to like & getrecommendations! Published in 2020 at "Pediatrics"
DOI: 10.1542/peds.2020-023861rrrr
Abstract: DB Kohn, C Booth, EM Kang. Nature Med. 2020;26(2):200–206 To assess the safety and evaluate the efficacy and stability of ex vivo autologous CD34+ hematopoietic stem and progenitor cell based lentiviral gene therapy for X-linked… read more here.
Keywords: linked chronic; lentiviral gene; gene therapy; therapy linked ... See more keywords
Papulopustular Dermatitis in X-Linked Chronic Granulomatous Disease
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2018.00429
Abstract: Here we describe two term male infants diagnosed with X-linked CGD who present, in addition to frequent infection, with a unique papulopustular skin rash. CGD is caused by a number of genetic defects that impair… read more here.
Keywords: dermatitis linked; chronic granulomatous; linked chronic; papulopustular dermatitis ... See more keywords