Metabolic Blockade-Based Genome Mining Reveals Lipochain-Linked Dihydro-β-alanine Synthetases Involved in Autucedine Biosynthesis.
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DOI: 10.1021/acs.orglett.2c01957
Abstract: Continuously mining the Streptomyces olivaceus SCSIO T05 genome leads to the identification of new lipopeptides (autucedines A-C), constituting members of the 10th skeleton isolated from this strain. The corresponding biosynthetic gene cluster (aut) was verified… read more here.
Keywords: metabolic blockade; based genome; blockade based; dihydro alanine ... See more keywords