Characterization of glycan substrates accumulating in GM1 Gangliosidosis
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics and Metabolism Reports"
DOI: 10.1016/j.ymgmr.2019.100524
Abstract: Introduction GM1 gangliosidosis is a rare autosomal recessive genetic disorder caused by the disruption of the GLB1 gene that encodes β-galactosidase, a lysosomal hydrolase that removes β-linked galactose from the non-reducing end of glycans. Deficiency… read more here.
Keywords: glycan metabolites; glb1; gangliosidosis; gm1 gangliosidosis ... See more keywords
Novel chlorophyll a derivatives with ester-linked galactose fragments for photodynamic therapy and fluorescence diagnostics of cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Porphyrins and Phthalocyanines"
DOI: 10.1142/s1088424621500048
Abstract: In the present work, a number of chlorophyll [Formula: see text] derivatives were synthetized with galactose fragments with an ester bond between macrocycle and carbohydrate fragments. It showed that synthesized compounds fluoresce intensely inside HeLa… read more here.
Keywords: chlorophyll derivatives; novel chlorophyll; galactose fragments; derivatives ester ... See more keywords