The X-linked helicase DDX3X is required for lymphoid differentiation and MYC-driven lymphomagenesis.
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DOI: 10.1158/0008-5472.can-21-2454
Abstract: The X-linked gene DDX3X encodes an RNA helicase that is mutated at high frequencies in several types of human B-cell lymphoma. Females have two active DDX3X alleles and males carry a DDX3Y homolog on the… read more here.
Keywords: lymphomagenesis; driven lymphomagenesis; helicase ddx3x; ddx3x ... See more keywords