Linked Mutations at Adjacent Nucleotides Have Shaped Human Population Differentiation and Protein Evolution
Sign Up to like & getrecommendations! Published in 2019 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evz014
Abstract: Despite the fundamental importance of single nucleotide polymorphisms (SNPs) to human evolution, there are still large gaps in our understanding of the forces that shape their distribution across the genome. SNPs have been shown to… read more here.
Keywords: snps; linked mutations; evolution; human population ... See more keywords
Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability
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DOI: 10.1101/2022.09.09.507262
Abstract: Charcot-Marie-Tooth disease (CMT) is the most common inherited peripheral polyneuropathy in humans, and its subtypes are linked to mutations in dozens of different genes, including the gene coding for ganglioside-induced differentiation-associated protein 1 (GDAP1). The… read more here.
Keywords: cmt linked; gdap1; protein stability; cmt ... See more keywords
Mycotoxin-Linked Mutations and Cancer Risk: A Global Health Issue
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DOI: 10.3390/ijerph19137754
Abstract: Humans continue to be constantly exposed to mycotoxins, mainly through oral exposure (dietary), inhalation, or dermal contact. Recently, it has been of increasing interest to investigate mycotoxin-linked carcinogenicity. This systematic review was conducted to synthesize… read more here.
Keywords: cancer; risk; cancer risk; mycotoxin linked ... See more keywords