Estimation of Effective Concentrations Enforced by Complex Linker Architectures from Conformational Ensembles.
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DOI: 10.1021/acs.biochem.1c00737
Abstract: Proteins and protein assemblies often tether interaction partners to strengthen interactions, to regulate activity through auto-inhibition or -activation, or to boost enzyme catalysis. Tethered reactions are regulated by the architecture of the tether, which defines… read more here.
Keywords: effective concentrations; estimation effective; linker; effective concentration ... See more keywords