Articles with "linker chemistry" as a keyword



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Making smart drugs smarter: The importance of linker chemistry in targeted drug delivery

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Published in 2020 at "Medicinal Research Reviews"

DOI: 10.1002/med.21720

Abstract: Smart drugs, such as antibody‐drug conjugates, for targeted therapy rely on the ability to deliver a warhead to the desired location and to achieve activation at the same site. Thus, designing a smart drug often… read more here.

Keywords: delivery; chemistry; linker chemistry; drug ... See more keywords
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Site-specific labeling of an anti-MUC1 antibody: probing the effects of conjugation and linker chemistry on the internalization process

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Published in 2019 at "RSC Advances"

DOI: 10.1039/c8ra09902b

Abstract: Four antibody conjugates were prepared to investigate how the conjugation and linker chemistry would impact ADC endocytosis and intracellular trafficking. read more here.

Keywords: chemistry; conjugation linker; linker chemistry; antibody ... See more keywords