Investigating Ligand Binding to HCN Channels by Surface Plasmon Resonance
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.252
Abstract: Hyperpolarization-activated cyclic nucleotide-modulated (HCN) channels control cardiac and neuronal rhythmicity. HCN channels contain cyclic nucleotide-binding (CNB) domain in their C-terminal region linked to the pore-forming transmembrane segment with a C-linker. The C-linker couples the conformational… read more here.
Keywords: linker cnb; ligand binding; hcn channels; linker ... See more keywords