Articles with "linker responsive" as a keyword



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A Self-Immolative Linker for the pH-Responsive Release of Amides

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28062445

Abstract: The administration of therapeutics using bioconjugation has been mainly limited to drugs containing amine, alcohol, or thiol functional groups. Here, we report a general procedure for the preparation of benzylic N-acyl carbamates suitable for masking… read more here.

Keywords: immolative linker; linker responsive; release amides; self immolative ... See more keywords