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Application of Cleavable Linkers to Improve Therapeutic Index of Radioligand Therapies

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27154959

Abstract: Radioligand therapy (RLT) is an emergent drug class for cancer treatment. The dose administered to cancer patients is constrained by the radiation exposure to normal tissues to maintain an appropriate therapeutic index. When a radiopharmaceutical… read more here.

Keywords: cleavable linkers; application cleavable; therapeutic index; linkers improve ... See more keywords