Discovery of Diphenoxy Derivatives with Flexible Linkers as Ligands for β-amyloid Plaques.
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DOI: 10.1021/acs.molpharmaceut.0c00537
Abstract: The highly rigid and planar scaffolds with π-conjugated systems have been widely considered to be indispensable for Aβ binding ligands. In this study, a library of diphenoxy compounds with different types of more flexible linkers… read more here.
Keywords: flexible linkers; derivatives flexible; discovery diphenoxy; ligands amyloid ... See more keywords