Succinylation Links Metabolism to Protein Functions
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemical Research"
DOI: 10.1007/s11064-019-02780-x
Abstract: Post-translational modifications (PTMs) are important regulators of protein function, and integrate metabolism with physiological and pathological processes. Phosphorylation and acetylation are particularly well studied PTMs. A relatively recently discovered novel PTM is succinylation in which… read more here.
Keywords: metabolism protein; succinylation; metabolism; succinylation links ... See more keywords
Epigenomic links from metabolism-methionine and chromatin architecture.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in chemical biology"
DOI: 10.1016/j.cbpa.2021.01.011
Abstract: Chromatin and associated epigenetic marks provide important platforms for gene regulation in response to metabolic changes associated with environmental exposures, including physiological stress, nutritional deprivation, and starvation. Numerous studies have shown that fluctuations of key… read more here.
Keywords: chromatin; methionine; epigenomic links; metabolism methionine ... See more keywords
Histone Acetyltransferase 1 Links Metabolism and Transcription to Cell-Cycle Progression.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.08.004
Abstract: HAT1 is an essential gene in mammals that acetylates newly synthesized histone H4 and is involved in chromatin assembly and genome maintenance. In this issue of Molecular Cell, Gruber et al. (2019) show that HAT1 binds… read more here.
Keywords: links metabolism; metabolism transcription; histone acetyltransferase; acetyltransferase links ... See more keywords
Lysine Malonylation and Its Links to Metabolism and Diseases
Sign Up to like & getrecommendations! Published in 2023 at "Aging and Disease"
DOI: 10.14336/ad.2022.0711
Abstract: Malonylation is a recently identified post-translational modification with malonyl-coenzyme A as the donor. It conserved both in prokaryotes and eukaryotes. Recent advances in the identification and quantification of lysine malonylation by bioinformatic analysis have improved… read more here.
Keywords: metabolism diseases; malonylation; lysine malonylation; links metabolism ... See more keywords