Editorial for “Subcutaneous Adipose Tissue Edema in Lipedema Revealed by Noninvasive 3T Magnetic Resonance Lymphangiography”
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28400
Abstract: Lipedema as one of rare adipose disorders 1 is characterized by excessively deposited subcutaneous adipose tissue (SAT) especially in the lower extremities, which has a distinctive female predilection and is often clinically misdiagnosed as obesity… read more here.
Keywords: lipedema; lymphangiography; edema; methodology ... See more keywords
SVF-derived extracellular vesicles carry characteristic miRNAs in lipedema
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-64215-w
Abstract: Lipedema is a chronic, progressive disease of adipose tissue with lack of consistent diagnostic criteria. The aim of this study was a thorough comparative characterization of extracellular microRNAs (miRNAs) from the stromal vascular fraction (SVF)… read more here.
Keywords: extracellular vesicles; lipedema; mir; mirnas lipedema ... See more keywords
A 10-Year Retrospective before-and-after Study of Lipedema Surgery: Patient-Reported Lipedema-Associated Symptom Improvement after Multistage Liposuction
Sign Up to like & getrecommendations! Published in 2022 at "Plastic and Reconstructive Surgery"
DOI: 10.1097/prs.0000000000008880
Abstract: Background: Despite an increasing demand for surgical treatment of lipedema, the evidence for liposuction is still limited. Little is known about the influence of disease stage, patient age, body mass index, or existing comorbidities on… read more here.
Keywords: lipedema associated; lipedema; surgery; liposuction ... See more keywords
A randomised controlled multicentre investigator-blinded clinical trial comparing efficacy and safety of surgery versus complex physical decongestive therapy for lipedema (LIPLEG)
Sign Up to like & getrecommendations! Published in 2021 at "Trials"
DOI: 10.1186/s13063-021-05727-2
Abstract: Background Lipedema is a chronic disorder of the adipose tissue that affects mainly women, characterised by symmetrical, excessive fatty tissue on the legs and pain. Standard conservative treatment is long-term comprehensive decongestive therapy (CDT) to… read more here.
Keywords: liposuction; trial; lipedema; decongestive therapy ... See more keywords
Dietary supplements for lipedema
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Preventive Medicine and Hygiene"
DOI: 10.15167/2421-4248/jpmh2022.63.2s3.2758
Abstract: Summary Lipedema is a chronic disease that mostly manifests in females as the abnormal distribution of subcutaneous adipose connective tissue, usually coupled with bruising, pain, and edema. Lipedema molecular pathophysiology is currently not clear, but… read more here.
Keywords: diet physical; lipedema; physical exercise; supplements lipedema ... See more keywords
Genetics of lipedema: new perspectives on genetic research and molecular diagnoses.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201907_18292
Abstract: OBJECTIVE The aim of this qualitative review is to provide an update on the current understanding of the genetic determinants of lipedema and to develop a genetic test to differentiate lipedema from other diagnoses. MATERIALS… read more here.
Keywords: new perspectives; lipedema new; genetics lipedema; lipedema ... See more keywords
Is subcutaneous adipose tissue expansion in people living with lipedema healthier and reflected by circulating parameters?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1000094
Abstract: Lipedema may be considered a model for healthy expandability of subcutaneous adipose tissue (SAT). This condition is characterized by the disproportional and symmetrical SAT accumulation in the lower-body parts and extremities, avoiding the abdominal area.… read more here.
Keywords: lipedema; subcutaneous adipose; adipose tissue; circulating parameters ... See more keywords
A distinct M2 macrophage infiltrate and transcriptomic profile decisively influence adipocyte differentiation in lipedema
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1004609
Abstract: Lipedema is a chronic and progressive adipose tissue disorder, characterized by the painful and disproportionate increase of the subcutaneous fat in the lower and/or upper extremities. While distinct immune cell infiltration is a known hallmark… read more here.
Keywords: lipedema; distinct macrophage; adipose tissue; differentiation ... See more keywords
Multi-Level Analysis of Adipose Tissue Reveals the Relevance of Perivascular Subpopulations and an Increased Endothelial Permeability in Early-Stage Lipedema
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10051163
Abstract: Lipedema is a chronic, progressive disease of adipose tissue with unknown etiology. Based on the relevance of the stromal vascular fraction (SVF) cell population in lipedema, we performed a thorough characterization of subcutaneous adipose tissue,… read more here.
Keywords: stage lipedema; early stage; lipedema; adipose tissue ... See more keywords
Current Mechanistic Understandings of Lymphedema and Lipedema: Tales of Fluid, Fat, and Fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23126621
Abstract: Lymphedema and lipedema are complex diseases. While the external presentation of swollen legs in lower-extremity lymphedema and lipedema appear similar, current mechanistic understandings of these diseases indicate unique aspects of their underlying pathophysiology. They share… read more here.
Keywords: lipedema; lymphedema lipedema; current mechanistic; mechanistic understandings ... See more keywords
Lipedema Research—Quo Vadis?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm13010098
Abstract: When studying the current literature, one might get the impression that lipedema is a “modern” disease, with increasing incidence and augmenting prevalence throughout Western countries during the last decade. However, a quick look into older… read more here.
Keywords: research quo; lipedema; disease; quo vadis ... See more keywords