Downregulation of adipose triglyceride lipase by EB viral‐encoded LMP2A links lipid accumulation to increased migration in nasopharyngeal carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12824
Abstract: Epstein–Barr virus (EBV)‐associated nasopharyngeal carcinoma (NPC) is one of the most common human cancers in South‐East Asia exhibiting typical features of lipid accumulation. EBV‐encoded latent membrane protein 2A (LMP2A) is expressed in most NPCs enhancing… read more here.
Keywords: accumulation; lipid accumulation; migration; downregulation ... See more keywords
Effect of atorvastatin on lipoxygenase pathway‐related gene expression in an in vitro model of lipid accumulation in hepatocytes
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13552
Abstract: Lipid accumulation in hepatocytes can result from an imbalance between lipid acquisition and lipid catabolism. In recent years, it has been discovered that eicosanoids derived from arachidonic acid (AA) have the potential to create specialized… read more here.
Keywords: vitro model; lipoxygenase pathway; lipid accumulation; expression ... See more keywords
Mechanism of the oxidative stress‐mediated increase in lipid accumulation by the bacterium, R. opacus PD630: Experimental analysis and genome‐scale metabolic modeling
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27330
Abstract: Appropriate species of oleaginous bacteria, with their high growth rates and lipid accumulation capabilities, can be good contenders for industrial triacylglycerol (TAG) production, compared to microalgae. Further, oxidative stress (OS) can be used to significantly… read more here.
Keywords: accumulation; mechanism; lipid accumulation; increase ... See more keywords
miR‐497 accelerates oxidized low‐density lipoprotein‐induced lipid accumulation in macrophages by repressing the expression of apelin
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10808
Abstract: microRNAs (miRNAs) play important roles in the pathogenesis of atherosclerosis. A previous study has reported that miR‐497 is elevated in advanced atherosclerotic lesions in an apoE‐deficient (apoE‐/‐) mouse model. The purpose of this study is… read more here.
Keywords: lipid accumulation; apelin; mir; mir 497 ... See more keywords
PDE4 inhibitor Roflumilast modulates inflammation and lipid accumulation in PCOS mice to improve ovarian function and reduce DHEA‐induced granulosa cell apoptosis in vitro
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development Research"
DOI: 10.1002/ddr.22027
Abstract: This study was implemented to address the role of Roflumilast in polycystic ovary syndrome (PCOS) as well as to discuss its reaction mechanism in vivo and in vitro. In vivo, mice were administrated with 6 mg… read more here.
Keywords: dhea induced; pcos mice; lipid accumulation; mice ... See more keywords
Regulation of lipid accumulation in Schizochytrium sp. ATCC 20888 in response to different nitrogen sources
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Lipid Science and Technology"
DOI: 10.1002/ejlt.201700025
Abstract: Summary Regulation of lipid accumulation in Schizochytrium sp. ATCC 20888 in response to different nitrogen sources was investigated in this study. Nitrogen sources had important effects on the cell growth, lipid accumulation and docosahexaenoic acid… read more here.
Keywords: nitrogen; nitrogen sources; accumulation schizochytrium; lipid accumulation ... See more keywords
Silencing of IGF2BP1 restrains ox-LDL-induced lipid accumulation and inflammation by reducing RUNX1 expression and promoting autophagy in macrophages.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.22994
Abstract: Atherosclerosis (AS) is a chronic inflammatory disease with the formation and accumulation of macrophage-derived foam cells in the subendothelial space of blood vessels as one major characteristic. Insulin-like growth factor 2 messenger RNA (mRNA) binding… read more here.
Keywords: expression; accumulation; silencing igf2bp1; lipid accumulation ... See more keywords
Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28578
Abstract: Morin (MO), a natural bioflavinoid, exists in many herbs. Previous studies have acclaimed MO's anti‐inflammatory, antidiabetic, antioxidant, antifibrotic, anticancer, and antihyperglycemic biological effects. This study aimed to assess the molecular mechanism of MO involved in… read more here.
Keywords: accumulation; lipid accumulation; tyloxapol induced; hepg2 cell ... See more keywords
Lactobacillus plantarum HF02 alleviates lipid accumulation and intestinal microbiota dysbiosis in high-fat diet-induced obese mice.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12538
Abstract: BACKGROUND Obesity is closely associated with lipid accumulation and intestinal microbiota dysbiosis. It has been proved that probiotics supplement contributes to alleviate obesity. The objective of this study was to investigate the mechanism by which… read more here.
Keywords: hf02; intestinal microbiota; obese mice; accumulation ... See more keywords
Vitamin D Deficiency Attenuates Acute Alcohol-Induced Hepatic Lipid Accumulation in Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Lipids"
DOI: 10.1002/lipd.12188
Abstract: Vitamin D deficiency has been frequently reported in chronic liver disease. However, its influence on hepatic lipid accumulation in alcoholic liver disease remains unclear. The present study investigated the effects of vitamin D deficiency on… read more here.
Keywords: hepatic lipid; lipid accumulation; alcohol induced; deficiency ... See more keywords
Effects of fatty acid-ethanol amine (FA-EA) derivatives on lipid accumulation and inflammation.
Sign Up to like & getrecommendations! Published in 2023 at "Lipids"
DOI: 10.1002/lipd.12368
Abstract: This study aimed to investigate the effect of fatty acid-ethanol amine (FA-EA) derivatives (L1-L10) on the mitigation of intracellular lipid accumulation and downregulation of pro-inflammatory cytokines in vitro. First, the series of FA-EA derivatives were… read more here.
Keywords: acid ethanol; accumulation; lipid accumulation; amine derivatives ... See more keywords