Endogenous lipid antigens for invariant natural killer T cells hold the reins in adipose tissue homeostasis
Sign Up to like & getrecommendations! Published in 2018 at "Immunology"
DOI: 10.1111/imm.12839
Abstract: The global obesity epidemic and its associated co‐morbidities, including type 2 diabetes, cardiovascular disease and certain types of cancers, have drawn attention to the pivotal role of adipocytes in health and disease. Besides their ‘classical’… read more here.
Keywords: lipid antigens; invariant natural; inkt cells; adipose tissue ... See more keywords
Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T-cells.
Sign Up to like & getrecommendations! Published in 2023 at "JCI insight"
DOI: 10.1172/jci.insight.158089
Abstract: Invariant natural killer T (iNKT) cells act at the interface between lipid metabolism and immunity because of their restriction to lipid antigens presented on CD1d by antigen-presenting cells (APCs). How foreign lipid antigens are delivered… read more here.
Keywords: activation; lipid antigens; antigen delivery; antigen ... See more keywords