Transgenic manipulation of triacylglycerol biosynthetic enzymes in B. napus alters lipid-associated gene expression and lipid metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-07387-x
Abstract: Oilseed rape ( Brassica napus ) is an important crop that is cultivated for the oil (mainly triacylglycerol; TAG) it produces in its seeds. TAG synthesis is controlled mainly by key enzymes in the Kennedy… read more here.
Keywords: expression; lipid metabolism; associated gene; gene expression ... See more keywords
Characteristics of plaque lipid-associated macrophages and their possible roles in the pathogenesis of atherosclerosis
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DOI: 10.1097/mol.0000000000000842
Abstract: Purpose of review Recent findings from single-cell transcriptomic studies prompted us to revisit the role of plaque foamy macrophages in the pathogenesis of atherosclerosis. In this review, we compared the gene expression profile of plaque… read more here.
Keywords: plaque foamy; foamy macrophages; associated macrophages; pathogenesis atherosclerosis ... See more keywords
Lipid-associated macrophages are induced by cancer-associated fibroblasts and mediate immune suppression in breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-22-1427
Abstract: Tumor-associated macrophages (TAM) play a detrimental role in triple-negative breast cancer (TNBC). In-depth analysis of TAM characteristics and interactions with stromal cells, such as cancer-associated fibroblast (CAF), could provide important biological and therapeutic insights. Here… read more here.
Keywords: breast cancer; associated macrophages; cancer associated; lipid associated ... See more keywords