Nanostructured Lipid-based Films for Substrate Mediated Applications in Biotechnology.
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DOI: 10.1002/adfm.201704356
Abstract: Amphiphilic in nature, lipids spontaneously self-assemble into a range of nanostructures in the presence of water. Among lipid self-assembled structures, liposomes and supported lipid bilayers have long held scientific interest for their main applications in… read more here.
Keywords: substrate mediated; lipid based; applications biotechnology; based films ... See more keywords
The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability and Safety of Lipid-Based Nanoparticles for mRNA and DNA Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203022
Abstract: Lipid-based nanoparticles have recently shown great promise, establishing themselves as the gold standard in delivering novel RNA therapeutics. However, research on the effects of storage on their efficacy, safety and stability is still lacking. Here,… read more here.
Keywords: storage conditions; based nanoparticles; lipid based; stability ... See more keywords
Lipid-based Nanocarriers Enabled Oral Delivery of Oleanolic Acid Derivative DKS26 for Diabetes Management.
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DOI: 10.1002/adhm.202300639
Abstract: Oleanolic acid (OA, (3β)-3-hydroxy-oleanol-12-en-28-oic acid) derivative DKS26 has hypolipidemic, islet and hepatoprotective effects. However, high lipophilicity and low water solubility of DKS26 led to its extremely low oral bioavailability. Herein, lipid-based nanocarriers, including lipid nanodiscs… read more here.
Keywords: dks26; lipid based; acid derivative; based nanocarriers ... See more keywords
Advancing the Pharmaceutical Potential of Bioinorganic Hybrid Lipid‐Based Assemblies
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DOI: 10.1002/advs.201800564
Abstract: Abstract Bioinspired lipid assemblies that mimic the elaborate architecture of natural membranes have fascinated researchers for a long time. These lipid assemblies have gone from being just an imperative platform for biophysical research to a… read more here.
Keywords: hybrid lipid; lipid based; pharmaceutical potential; bioinorganic hybrid ... See more keywords
DNA-Directed Patterning for Versatile Validation and Characterization of a Lipid-Based Nanoparticle Model of SARS-CoV-2.
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DOI: 10.1002/advs.202101166
Abstract: Lipid-based nanoparticles have been applied extensively in drug delivery and vaccine strategies and are finding diverse applications in the coronavirus disease 2019 (COVID-19) pandemic-from vaccine-component encapsulation to modeling the virus, itself. High-throughput, highly flexible methods… read more here.
Keywords: directed patterning; based nanoparticle; lipid based; sars cov ... See more keywords
Ligand conjugated lipid‐based nanocarriers for cancer theranostics
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28205
Abstract: Cancer is one of the major health‐related issues affecting the population worldwide and subsequently accounts for the second‐largest death. Genetic and epigenetic modifications in oncogenes or tumor suppressor genes affect the regulatory systems that lead… read more here.
Keywords: conjugated lipid; lipid based; ligand conjugated; cancer ... See more keywords
Comparisons between a self‐microemulsifying system and lipid nanoparticles of oxyresveratrol on the physicochemical properties and Caco‐2 cell permeability
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DOI: 10.1002/ejlt.201600053
Abstract: The lipid-based formulations including an oily self-microemulsifying drug delivery system (SMEDDS), solid lipid nanoparticles (SLN), and nanostructured lipid carriers (NLC) were developed for the oral delivery of oxyresveratrol (OXYR). Each system was successfully formulated using… read more here.
Keywords: oxyr; self microemulsifying; lipid based; permeability ... See more keywords
Lipid‐based strategies used to identify extracellular vesicles in flow cytometry can be confounded by lipoproteins: Evaluations of annexin V, lactadherin, and detergent lysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12200
Abstract: Abstract Flow cytometry (FCM) is a popular method used in characterisation of extracellular vesicles (EVs). Circulating EVs are often identified by FCM by exploiting the lipid nature of EVs by staining with Annexin V (Anx5)… read more here.
Keywords: extracellular vesicles; lysis; flow cytometry; evs ... See more keywords
Transferrin-Modified Vitamin-E/Lipid Based Polymeric Micelles for Improved Tumor Targeting and Anticancer Effect of Curcumin
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutical Research"
DOI: 10.1007/s11095-018-2382-9
Abstract: PurposeTransferrin receptor (TfR) is up-regulated in various malignant tumors not only to meet the iron requirement, but also to increase the cell survival via participation in various cellular signaling pathways. Here we explored transferrin as… read more here.
Keywords: micelles improved; lipid based; cvpm; modified vitamin ... See more keywords
An Overview of 3D Printing Technologies for Soft Materials and Potential Opportunities for Lipid-based Drug Delivery Systems
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DOI: 10.1007/s11095-018-2531-1
Abstract: PurposeThree-dimensional printing (3DP) is a rapidly growing additive manufacturing process and it is predicted that the technology will transform the production of goods across numerous fields. In the pharmaceutical sector, 3DP has been used to… read more here.
Keywords: technologies soft; soft materials; lipid based; drug delivery ... See more keywords
Current approaches in lipid-based nanocarriers for oral drug delivery
Sign Up to like & getrecommendations! Published in 2021 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-021-00908-7
Abstract: Graphical abstract Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral bioavailability because of their remarkable advantages like low toxicity, affordable scale-up manufacture, strong biocompatibility or high drug loading efficiency. The… read more here.
Keywords: drug delivery; lipid based; oral drug; based nanocarriers ... See more keywords