Nano-engineered nerolidol loaded lipid carrier delivery system attenuates cyclophosphamide neurotoxicity – Probable role of NLRP3 inflammasome and caspase-1
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2020.113464
Abstract: Neuroinflammation is one of the most common etiology in various neurological disorders and responsible for multi-array neurotoxic manifestations such as neurodegeneration, neurotransmitters alteration and cognitive dysfunction. NR (Nerolidol) is a natural bioactive molecule which possesses… read more here.
Keywords: caspase; lipid carrier; nlrp3 inflammasome; inflammasome caspase ... See more keywords
Near‐infrared light‐triggered drug release from a multiple lipid carrier complex using an all‐in‐one strategy
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2017.06.029
Abstract: Abstract The present study reports a drug delivery system comprising nanostructured lipid carrier (NLCs) within liposomes (Lip‐NLCs). This multiple lipid carrier complex features laser‐triggered responsive drug release. Both hydrophobic and hydrophilic drugs can be loaded… read more here.
Keywords: lip nlcs; drug; lipid carrier; drug release ... See more keywords
A proof-of-concept for developing oral lipidized peptide Nanostructured Lipid Carrier formulations
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.101394
Abstract: Abstract The aim of the study was to develop a protocol to encapsulate lipidized-peptides in Nanostructured Lipid Carrier (NLC) by High Pressure Homogenization (HPH) for oral delivery. The impact of composition, pressure and number of… read more here.
Keywords: concept developing; hip; lipid carrier; proof concept ... See more keywords
Nanostructured lipid carrier (NLC)-based novel hydrogels as potential carriers for nepafenac applied after cataract surgery for the treatment of inflammation: design, characterization and in vitro cellular inhibition and uptake studies
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra00552k
Abstract: The objective of this study was to design innovative nanostructured lipid carrier (NLC) nanoparticle-loaded hydrogels for drug delivery of nepafenac (NP) applied after cataract surgery for the treatment of postoperative inflammation. NP-NLC nanoparticles were prepared… read more here.
Keywords: treatment; inflammation; lipid carrier; carrier ... See more keywords
Efficiency of brown seaweed (Sargassum longifolium) polysaccharides encapsulated in nanoemulsion and nanostructured lipid carrier against colon cancer cell lines HCT 116
Sign Up to like & getrecommendations! Published in 2018 at "RSC Advances"
DOI: 10.1039/c8ra02616e
Abstract: Bioactive polysaccharides extracted from brown seaweeds have potent antioxidant, antitumor, antibacterial, antiviral, anti-inflammatory activities and nanomedicine applications. In the present study, we have made an attempt to overcome the instability and bioavailability problem of exopolysaccharides… read more here.
Keywords: brown seaweed; lipid carrier; nanoemulsion; nanoemulsion nanostructured ... See more keywords
Development, optimization, and evaluation of a nanostructured lipid carrier of sesame oil loaded with miconazole for the treatment of oral candidiasis
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2021.2023703
Abstract: Abstract Candida albicans is the fungus responsible for oral candidiasis, a prevalent disease. The development of antifungal-based delivery systems has always been a major challenge for researchers. This study was designed to develop a nanostructured… read more here.
Keywords: nanostructured lipid; oral candidiasis; candidiasis; oil loaded ... See more keywords
Topical delivery of Bruton’s tyrosine kinase inhibitor and curcumin-loaded nanostructured lipid carrier gel: Repurposing strategy for the psoriasis management
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2142610
Abstract: Abstract This work investigates the synergistic potential of the nanostructured lipid carrier (NLC) gel of Ibrutinib with Curcumin as a repurposing strategy to treat psoriasis. In the present work, various components such as liquid lipid,… read more here.
Keywords: nanostructured lipid; repurposing strategy; curcumin; gel ... See more keywords
Zerumbone-Loaded Nanostructured Lipid Carrier Gel Enhances Wound Healing in Diabetic Rats
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/1129297
Abstract: This study investigated the healing effects of topical application of zerumbone, a well-known anti-inflammatory compounds loaded on nanostructured lipid carrier gel (Carbopol 940) (ZER-NLCG) on excisional wounds in streptozotocin-induced diabetic rats. Diabetic rats with inflicted… read more here.
Keywords: loaded nanostructured; carrier gel; nanostructured lipid; diabetic rats ... See more keywords
Nanostructured Lipid Carrier-Based Delivery of Pioglitazone for Treatment of Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.934156
Abstract: Pioglitazone (PGZ) is utilized as a therapeutic agent in the management of (type 2) diabetes to control blood glucose levels. The existing research work was intended to make and optimize PGZ-containing NLCs (nanostructured lipid carriers).… read more here.
Keywords: nanostructured lipid; pgz nlcs; type diabetes; lipid carrier ... See more keywords
Development of Computational In Silico Model for Nano Lipid Carrier Formulation of Curcumin
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28041833
Abstract: The oral delivery system is very important and plays a significant role in increasing the solubility of drugs, which eventually will increase their absorption by the digestive system and enhance the drug bioactivity. This study… read more here.
Keywords: carrier; nano lipid; curcumin; drug carrier ... See more keywords
Hypolipidemic Activity of Olive Oil-Based Nanostructured Lipid Carrier Containing Atorvastatin
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12132160
Abstract: Currently, hyperlipidemia is a growing health issue that is considered a risk factor for obesity. Controlling body weight and modifying life style in most of cases are not adequate and the condition requires medical treatment.… read more here.
Keywords: nanostructured lipid; formulation; oil; hypolipidemic activity ... See more keywords