Articles with "lipid carriers" as a keyword



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Arginine‐Modified Nanostructured Lipid Carriers with Charge‐Reversal and pH‐Sensitive Membranolytic Properties for Anticancer Drug Delivery

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Published in 2017 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.201600693

Abstract: The ability to escape endo/lysosomal trafficking is critically important to prevent entrapment of nanomedicines in lysosomes and to achieve maximum therapeutic efficacy of drugs delivered to cells through endocytosis. In this study, a novel pH-sensitive… read more here.

Keywords: lipid carriers; charge reversal; microscopy; drug delivery ... See more keywords
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Development of Nanostructured Lipid Carriers (NLCs) Using Pumpkin and Kenaf Seed Oils with Potential Photoprotective and Antioxidative Properties

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Published in 2019 at "European Journal of Lipid Science and Technology"

DOI: 10.1002/ejlt.201900082

Abstract: Both pumpkin and kenaf seed oil with carnauba wax (CW) and beeswax (BW) are used to develop nanostructured lipid carriers (NLCs) loaded with Uvinul T150 and Uvinul A Plus Granular for a UV protection formulation.… read more here.

Keywords: carriers nlcs; lipid carriers; pumpkin kenaf; kenaf seed ... See more keywords
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Sirolimus‐ and cyclosporine‐loaded nanostructured lipid carriers: Development, characterization, and in vitro evaluation in T‐cell profiles of patients with a history of recurrent pregnancy loss

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Published in 2023 at "Reproductive Medicine and Biology"

DOI: 10.1002/rmb2.12509

Abstract: Abstract Purpose The authors developed nanostructured lipid carriers (NLCs) loaded with sirolimus (SRL) and cyclosporine (CsA) to improve their therapeutic efficacy in recurrent pregnancy loss (RPL) patients. Methods Mono‐delivery and co‐delivery of SRL and CsA… read more here.

Keywords: nanostructured lipid; nlcs nlcs; lipid carriers; recurrent pregnancy ... See more keywords
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Encapsulation of clove oil in nanostructured lipid carriers from natural waxes: Preparation, characterization and in vitro evaluation of the cholinesterase enzymes

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Published in 2019 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"

DOI: 10.1016/j.colsurfa.2019.123879

Abstract: Abstract Eugenol is a phenolic compound largely found in the clove essential oil that possesses promising biological activity. However, its low water solubility is a major concern and encapsulation is an alternative to improve water… read more here.

Keywords: lipid carriers; nanostructured lipid; oil; clove oil ... See more keywords
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Transport mechanism of chitosan‐N‐acetylcysteine, chitosan oligosaccharides or carboxymethyl chitosan decorated coumarin‐6 loaded nanostructured lipid carriers across the rabbit ocular

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Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"

DOI: 10.1016/j.ejpb.2017.08.013

Abstract: ABSTRACT To facilitate the hydrophobic drugs modeled by coumarin‐6 (Cou‐6) acrossing the cornea to the anterior chamber of the rabbit eye, chitosan (CS) derivatives including chitosan‐N‐acetyl‐l‐cysteine (CS‐NAC), chitosan oligosaccharides (COS) and carboxymethyl chitosan (CMCS) modified… read more here.

Keywords: lipid carriers; carboxymethyl chitosan; chitosan; chitosan oligosaccharides ... See more keywords
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Nanostructured lipid carriers versus solid lipid nanoparticles for the potential treatment of pulmonary hypertension via nebulization

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Published in 2018 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2018.10.003

Abstract: &NA; With the non‐selective vasodilating action, short half‐life and first‐pass metabolism of sildenafil (SC), local application in the lung for pulmonary arterial hypertension is of high demand. Although several nanosystems have been lately investigated, nanostructured… read more here.

Keywords: lipid carriers; carriers versus; nebulization; nanostructured lipid ... See more keywords
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Fabrication, characterization, and performance of antimicrobial alginate-based films containing thymol-loaded lipid nanoparticles: Comparison of nanoemulsions and nanostructured lipid carriers.

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Published in 2022 at "International journal of biological macromolecules"

DOI: 10.1016/j.ijbiomac.2022.03.149

Abstract: Antimicrobial biopolymer films were prepared by incorporating thymol-loaded nanostructured lipid carriers (NLC) or nanoemulsions (NE) into Ca-alginate solutions. Thymol-loaded-NLCs with thymol/lipid mass ratios of 0.1 and 0.2 were prepared and then used to fabricate NLC/alginate… read more here.

Keywords: nanostructured lipid; film; thymol; thymol loaded ... See more keywords
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Quality by Design (QbD)-enabled development of aceclofenac loaded-nano structured lipid carriers (NLCs): An improved dermatokinetic profile for inflammatory disorder(s).

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Published in 2017 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2016.12.010

Abstract: Present study was designed to prepare and characterize aceclofenac loaded nanostructured lipid carriers (NLCs) employing Quality by Design (QbD)-oriented approach. The NLCs were evaluated for their transdermal penetration potential and stability. Aceclofenac loaded nanostructured lipid… read more here.

Keywords: lipid carriers; quality; quality design; aceclofenac loaded ... See more keywords
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Enhanced brain delivery with lower hepatic exposure of lazaroid loaded nanostructured lipid carriers developed using a design of experiment approach☆

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Published in 2018 at "International Journal of Pharmaceutics"

DOI: 10.1016/j.ijpharm.2018.04.046

Abstract: Graphical abstract Figure. No Caption available. Abstract The current study was designed to develop and optimize lazaroid loaded nano‐structured lipid carriers (LAZ‐NLCs) using design of experiment approach for enhancing lazaroid brain exposure. Response surface plots… read more here.

Keywords: lipid carriers; using design; exposure; laz nlcs ... See more keywords
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Nanostructured lipid carriers containing Amphotericin B: Development, in vitro release assay, and storage stability

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Published in 2018 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2018.10.003

Abstract: Abstract Nanostructured-lipid-carriers (NLC) can improve the encapsulation rate and the stability of drugs. The aim of this study was to develop an amphotericin B (AmB)-containing-NLC (AmB-NLC). An experimental design was applied in order to determine… read more here.

Keywords: lipid carriers; vitro release; stability; amb ... See more keywords
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Repositioning miconazole nitrate for malaria: Formulation of sustained release nanostructured lipid carriers, structure characterization and in vivo antimalarial evaluation

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Published in 2020 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2020.102125

Abstract: Abstract It has been previously claimed that miconazole (MNZ) has activity against Plasmodium falciparum in vitro. Therefore, this study aims to evaluate the potential of MNZ as an alternative antimalarial agent. MNZ was entrapped in… read more here.

Keywords: lipid carriers; mnz; repositioning miconazole; vivo antimalarial ... See more keywords