Dual Functioned Hexapeptide-Coated Lipid-Core Nanomicelles Suppress Toll-Like Receptor-Mediated Inflammatory Responses through Endotoxin Scavenging and Endosomal pH Modulation.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202301230
Abstract: Excessive activation of Toll-like receptor (TLR) signaling pathways and the circulating endotoxin are key players in the pathogenesis of many acute and chronic inflammatory diseases. Regulation of TLR-mediated inflammatory responses by bioactive nanodevices represents a promising… read more here.
Keywords: core nanomicelles; like receptor; toll like; lipid core ... See more keywords
The utility of total lipid core burden index/maximal lipid core burden index ratio within the culprit plaque to predict filter-no reflow: insight from near-infrared spectroscopy with intravascular ultrasound
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-018-1697-z
Abstract: Filter-no reflow (FNR) is a phenomenon wherein flow improves after the retrieve of distal protection. Near-infrared spectroscopy with intravascular ultrasound (NIRS–IVUS) enables lipid detection. We evaluated the predictors of FNR during PCI using NIRS–IVUS. Thirty-two… read more here.
Keywords: fnr group; index; lipid core; spectroscopy ... See more keywords
Impact of pullback speed on evaluation of lipid core plaque using near-infrared spectroscopy-intravascular ultrasound
Sign Up to like & getrecommendations! Published in 2025 at "Cardiovascular Intervention and Therapeutics"
DOI: 10.1007/s12928-025-01124-7
Abstract: Near-infrared spectroscopy-intravascular ultrasound (NIRS-IVUS) can assess the amount of lipid core plaque, and the latest generation catheter allows for imaging at several different pullback speeds. The purpose of this study was to investigate the impact… read more here.
Keywords: spectroscopy; location maxlcbi4mm; core plaque; pullback ... See more keywords
Lipid-core nanocapsules increase the oral efficacy of quercetin in cutaneous leishmaniasis
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DOI: 10.1017/s003118201700097x
Abstract: SUMMARY New oral treatments are needed for all forms of leishmaniasis. Here, the improved oral efficacy of quercetin (Qc) and its penta-acetylated derivative (PQc) was evaluated in cutaneous leishmaniasis after encapsulation in lipid-core nanocapsules (LNCs)… read more here.
Keywords: efficacy quercetin; efficacy; lipid core; oral efficacy ... See more keywords
Artemether-loaded polymeric lipid-core nanocapsules reduce cell viability and alter the antioxidant status of U-87 MG cells
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2128819
Abstract: Abstract Glioblastomas are tumors that present a high mortality rate. Artemether (ART) is a lactone with antitumor properties, demonstrating low bioavailability and water solubility. In the present study, we developed lipid-core nanocapsules (LNC) containing pequi… read more here.
Keywords: antioxidant status; core nanocapsules; viability; lipid core ... See more keywords
Abstract 4139715: The impact of CSL112 and atorvastatin on lipid core stiffness in murine atherosclerotic plaques
Sign Up to like & getrecommendations! Published in 2024 at "Circulation"
DOI: 10.1161/circ.150.suppl_1.4139715
Abstract: Background: Plaque structural stress (PSS) is the stress within the body of atherosclerotic plaques, resulting from the dilation and stretching of vessels due to arterial pressure. Plaque rupture often occurs at sites of elevated PSS,… read more here.
Keywords: lipid cores; atherosclerotic plaques; lipid core; stiffness ... See more keywords
Jak-ing Up the Plaque's Lipid Core…and Even More.
Sign Up to like & getrecommendations! Published in 2018 at "Circulation Research"
DOI: 10.1161/circresaha.118.314074
Abstract: Until recently, many viewed atherosclerosis as a lipid storage disease or a bland accumulation of proliferated smooth muscle cells. How the landscape has changed! Abundant evidence now implicates intertwining pathways of inflammation as crucial to… read more here.
Keywords: ing plaque; core even; lipid core; jak ing ... See more keywords
Melatonin-loaded lipid-core nanocapsules protect against lipid peroxidation caused by paraquat through increased SOD expression in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2019 at "BMC Pharmacology & Toxicology"
DOI: 10.1186/s40360-019-0352-4
Abstract: Background Melatonin has been described in the literature as a potent antioxidant. However, melatonin presents variable, low bioavailability and a short half-life. The use of polymeric nanoparticulated systems has been proposed for controlled release. Thus,… read more here.
Keywords: core nanocapsules; lipid peroxidation; mel lnc; lipid core ... See more keywords
Arginylglycylaspartic Acid-Surface-Functionalized Doxorubicin-Loaded Lipid-Core Nanocapsules as a Strategy to Target Alpha(V) Beta(3) Integrin Expressed on Tumor Cells
Sign Up to like & getrecommendations! Published in 2017 at "Nanomaterials"
DOI: 10.3390/nano8010002
Abstract: Doxorubicin (Dox) clinical use is limited by dose-related cardiomyopathy, becoming more prevalent with increasing cumulative doses. Previously, we developed Dox-loaded lipid-core nanocapsules (Dox-LNC) and, in this study, we hypothesized that self-assembling and interfacial reactions could… read more here.
Keywords: core nanocapsules; rgd mcmn; lipid core; arginylglycylaspartic acid ... See more keywords