Design of temozolomide-loaded proliposomes and lipid crystal nanoparticles with industrial feasible approaches: comparative assessment of drug loading, entrapment efficiency, and stability at plasma pH
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DOI: 10.1080/08982104.2020.1748648
Abstract: Abstract Temozolomide is a drug approved for treating glioblastomas, which has 100% oral bioavailability but gets degraded at physiological pH thus having very short half-life and only 20–30% brain bioavailability. Due to its amphiphilic nature,… read more here.
Keywords: drug loading; entrapment efficiency; lipid crystal; crystal nanoparticles ... See more keywords