Comparative proteomic study of liver lipid droplets and mitochondria in mice housed at different temperatures
Sign Up to like & getrecommendations! Published in 2019 at "Febs Letters"
DOI: 10.1002/1873-3468.13509
Abstract: Laboratory mice are standardly housed at around 23 °C, setting them under chronic cold stress. Metabolic changes in the liver in mice housed at thermoneutral, standard and cold temperatures remain unknown. In the present study,… read more here.
Keywords: mice housed; study; comparative proteomic; droplets mitochondria ... See more keywords
The acyl‐CoA‐binding protein Acb1 regulates mitochondria, lipid droplets, and cell proliferation
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14415
Abstract: Mitochondria are involved in many cellular activities, including energy metabolism and biosynthesis of nucleotides, fatty acids and amino acids. Mitochondrial morphology is a key factor in dictating mitochondrial functions. Here, we report that the acyl‐CoA‐binding… read more here.
Keywords: binding protein; coa binding; lipid droplets; acb1 regulates ... See more keywords
The immunity-related GTPase IRGC mediates interaction between lipid droplets and mitochondria to facilitate sperm motility.
Sign Up to like & getrecommendations! Published in 2023 at "FEBS letters"
DOI: 10.1002/1873-3468.14640
Abstract: The immunity-related GTPases (IRGs) belong to the interferon-inducible GTPase protein family, which mediates cell-autonomous and innate immunity response to intracellular pathogens. Yet, the cellular and physiological function of IRGC, a member of the IRG subfamily,… read more here.
Keywords: immunity related; lipid droplets; immunity; sperm motility ... See more keywords
Facile Synthesis of Red/NIR AIE Luminogens with Simple Structures, Bright Emissions, and High Photostabilities, and Their Applications for Specific Imaging of Lipid Droplets and Image-Guided Photodynamic Therapy
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201704039
Abstract: Red/near-infrared (NIR) fluorescent molecules with aggregation-induced emission (AIE) characteristics are of great interest in bioimaging and therapeutic applications. However, their complicated synthetic approaches remain the major barrier to implementing these applications. Herein, a one-pot synthetic… read more here.
Keywords: red nir; bright emissions; aie luminogens; lipid droplets ... See more keywords
Raman spectroscopy-based insight into lipid droplets presence and contents in liver sinusoidal endothelial cells and hepatocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biophotonics"
DOI: 10.1002/jbio.201800290
Abstract: Liver sinusoidal endothelial cells (LSECs), a type of endothelial cells with unique morphology and function, play an important role in the liver hemostasis, and LSECs dysfunction is involved in the development of nonalcoholic fatty liver… read more here.
Keywords: sinusoidal endothelial; presence; liver sinusoidal; lipid droplets ... See more keywords
Effects of LPS on the accumulation of lipid droplets, proliferation, and steroidogenesis in goat luteinized granulosa cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.22329
Abstract: Lipopolysaccharide (LPS) can cause ovarian dysfunction and infertility in mammals. The purpose of this study was to investigate the effects of LPS on the accumulation of lipid droplets (LDs), proliferation, and steroidogenesis in goat luteinized… read more here.
Keywords: effects lps; accumulation; lps accumulation; accumulation lipid ... See more keywords
Fat, fight, and beyond: The multiple roles of lipid droplets in infections and inflammation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4mr0119-035r
Abstract: Increased accumulation of cytoplasmic lipid droplets (LDs) in host nonadipose cells is commonly observed in response to numerous infectious diseases, including bacterial, parasite, and fungal infections. LDs are lipid‐enriched, dynamic organelles composed of a core… read more here.
Keywords: immune response; response; fight beyond; beyond multiple ... See more keywords
Proteomics coupled transcriptomics reveals lipopolysaccharide inhibiting peroxisome proliferator-activated receptors signalling pathway to reduce lipid droplets accumulation in mouse liver.
Sign Up to like & getrecommendations! Published in 2023 at "Proteomics"
DOI: 10.1002/pmic.202300043
Abstract: Lipid droplets (LDs) are multifunctional organelles consisting of a central compartment of non-polar lipids shielded from the cytoplasm by a phospholipid monolayer. The excessive accumulation of LDs in cells is closely related to the development… read more here.
Keywords: peroxisome proliferator; proliferator activated; lipid droplets; mouse liver ... See more keywords
Exercising your fat (metabolism) into shape: a muscle-centred view
Sign Up to like & getrecommendations! Published in 2020 at "Diabetologia"
DOI: 10.1007/s00125-020-05170-z
Abstract: Fatty acids are an important energy source during exercise. Training status and substrate availability are determinants of the relative and absolute contribution of fatty acids and glucose to total energy expenditure. Endurance-trained athletes have a… read more here.
Keywords: metabolism; muscle; fatty acids; lipid droplets ... See more keywords
Lipid Droplets as Organelles.
Sign Up to like & getrecommendations! Published in 2018 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2017.12.007
Abstract: Long considered inert fat storage depots, it has become clear that lipid droplets (LDs) are bona fide organelles. Like other organelles, they have a characteristic complement of proteins and lipids, and undergo a life cycle… read more here.
Keywords: life cycle; lipid droplets; biology; droplets organelles ... See more keywords
Ultrastructural characterization of vitamin D receptors and metabolizing enzymes in the lipid droplets of the fatty liver in rat.
Sign Up to like & getrecommendations! Published in 2020 at "Acta Histochemica"
DOI: 10.1016/j.acthis.2020.151502
Abstract: Abstract Vitamin D is a steroid hormone with numerous actions in the organism. There are strong evidences that relate vitamin D deficiency with liver lipid metabolism disturbances, but the mechanism of this action is still… read more here.
Keywords: rat; microscopy; high sucrose; lipid droplets ... See more keywords